OBSERVATION METHOD AND OBSERVATION APPARATUS
    147.
    发明公开

    公开(公告)号:US20240303811A1

    公开(公告)日:2024-09-12

    申请号:US18598539

    申请日:2024-03-07

    Inventor: Ryo HASEBE

    Abstract: First, a biological sample is imaged, and a photographic image in which intensity values are distributed is acquired. After that, a localization region corresponding to an unusual part is extracted from the photographic image. At that time, a region of which intensity value satisfies a predetermined requirement in the photographic image is extracted as the localization region. Alternatively, the photographic image is input to a trained model created in advance, and a localization region output from the trained model is obtained. In this manner, the localization region corresponding to the unusual part can be extracted from the photographic image of the biological sample. This enables noninvasive observation of the unusual part of the biological sample without processing a cell by staining or the like.

    SYSTEMS, METHODS, AND APPARATUSES FOR LEARNING FOUNDATION MODELS FROM ANATOMY IN MEDICAL IMAGING FOR USE WITH MEDICAL IMAGE CLASSIFICATION AND SEGMENTATION

    公开(公告)号:US20240290076A1

    公开(公告)日:2024-08-29

    申请号:US18528675

    申请日:2023-12-04

    Abstract: Systems, methods, and apparatuses for learning foundation models from anatomy in medical imaging for use with medical image classification and/or image segmentation in the context of medical image analysis. Exemplary systems include means for receiving medical images; extracting human anatomical patterns from the medical images; generating a foundation model via learning the human anatomical patterns from within the medical images received, resulting in generic representations of the human anatomical patterns; wherein the learning includes: first learning prominent objects from within the medical images received corresponding to the human anatomical patterns; and secondly learning detailed parts within the learned prominent objects corresponding to sub-portions of the generic representations of the human anatomical patterns; wherein the learning further includes executing a self-supervised contrastive learning framework, including: executing an anatomy decomposer (AD) of the self-supervised contrastive learning framework which guides the generated foundation model to conserve hierarchical relationships of anatomical structures within the medical images received; and executing a purposive pruner (PP) of the self-supervised contrastive learning framework which forces the model to capture more distinct representations for different anatomical structures at varying granularity levels; and outputting the generated foundation model for use in processing medical images which form no part of the medical images received and used for training the generated foundation model.

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