公开(公告)号：US20110071766A1

公开(公告)日：2011-03-24

申请号：US12993260

申请日：2009-05-25

申请人： Kevin T. Dolan ,  Hubert Cecile Francois Martens

发明人： Kevin T. Dolan ,  Hubert Cecile Francois Martens

IPC分类号： G06F19/00

CPC分类号： G06K9/0053

摘要： A method is provided for determining a threshold (81, 82) for spike (12) detection in an electrophysiological signal (11). The method comprises a step of determining an estimated envelope (31) of the electrophysiological signal (11), a step of, based on the estimated envelope (31), determining an estimated Gaussian noise, a step of determining a distribution (51) of instantaneous amplitudes of the estimated Gaussian noise, a step of determining a mode (61) of the distribution (51) of instantaneous amplitudes, and determining the threshold (81, 82) based on the mode (61) of the distribution (51) of instantaneous amplitudes.

摘要翻译： 提供一种用于确定用于电生理信号（11）中的尖峰（12）检测的阈值（81,82）的方法。 该方法包括确定电生理信号（11）的估计包络（31）的步骤，基于估计包络（31），确定估计的高斯噪声的步骤，确定分布的分布（51）的步骤 估计高斯噪声的瞬时幅度，确定瞬时幅度分布（51）的模式（61）的步骤，以及基于分布（51）的模式（61）确定阈值（81,82） 瞬时振幅。

公开(公告)号：US07881501B2

公开(公告)日：2011-02-01

申请号：US11637760

申请日：2006-12-13

申请人： Charles Robert Pinnegar ,  Pierre Lemire ,  Ryan Kong ,  Doug Bird

发明人： Charles Robert Pinnegar ,  Pierre Lemire ,  Ryan Kong ,  Doug Bird

IPC分类号： G06K9/00 ,  G01V1/00 ,  H03F1/26

CPC分类号： G01V1/28 ,  G06K9/0053

摘要： The present invention relates to a method and system for processing multi-dimensional signal data to determine frequency dependent features therefrom. The multi-dimensional signal data are transformed into space-frequency or time-space-frequency domain, providing second signal data. At predetermined locations of at least a portion of the one of space and time-space of the second signal data a dominant feature corresponding to a largest value of the second signal data is determined. This is followed by the determination of a wave-vector corresponding to the dominant feature at each of the predetermined locations. Finally, a dip map, a frequency map, and an amplitude map are generated using the wave-vectors. The method and system for processing multi-dimensional signal data to determine frequency dependent features therefrom according to the present invention provide a powerful tool for improved and more detailed evaluation of seismic data using dip, frequency, and amplitude maps, resulting in substantially more accurate geophysical surveys.

摘要翻译： 本发明涉及一种用于处理多维信号数据以确定频率依赖特征的方法和系统。 多维信号数据被转换成空间频率或时空频域，提供第二信号数据。 在第二信号数据的空间和时间空间的至少一部分的预定位置处，确定与第二信号数据的最大值对应的主要特征。 接下来，确定与每个预定位置处的主要特征对应的波矢量。 最后，使用波矢量生成倾斜图，频率图和振幅图。 根据本发明的用于处理多维信号数据以确定其依赖于频率的特征的方法和系统为使用倾角，频率和幅度图改进和更详细地评估地震数据提供了强大的工具，导致基本上更准确的地球物理 调查。

公开(公告)号：US20100317932A1

公开(公告)日：2010-12-16

申请号：US12638658

申请日：2009-12-15

申请人： Teiji UKAWA

发明人： Teiji UKAWA

IPC分类号： A61B5/0205

CPC分类号： A61B5/0205 ,  A61B5/02028 ,  A61B5/02108 ,  A61B5/0215 ,  A61B5/0402 ,  A61B5/0535 ,  A61B5/0809 ,  A61B5/0836 ,  A61B5/087 ,  G06K9/0053

摘要： A respiratory function measuring apparatus includes: a first sensor configured to detect an invasive blood pressure; a second sensor configured to measure frequency of at least one of a heart beat and a respiration; and a controller configured to extract a respiratory function signal from the invasive blood pressure detected by the first sensor, by using at least one of the frequency measured by the second sensor and a harmonic of the frequency.

摘要翻译： 呼吸功能测量装置包括：第一传感器，被配置为检测侵入性血压; 被配置为测量心跳和呼吸中的至少一个的频率的第二传感器; 以及控制器，被配置为通过使用由第二传感器测量的频率和频率的谐波中的至少一个来从第一传感器检测到的有创血压中提取呼吸功能信号。

公开(公告)号：US20100145202A1

公开(公告)日：2010-06-10

申请号：US12530131

申请日：2008-03-07

申请人： James Andrew Mclaughlin ,  John McCune Anderson ,  Kenneth Anthony Kearney

发明人： James Andrew Mclaughlin ,  John McCune Anderson ,  Kenneth Anthony Kearney

IPC分类号： A61B5/0402

CPC分类号： G06K9/0053

摘要： A method of determining information concerning the identity of an individual comprising measuring at least one biometric of the individual comprising at least one bio-potential waveform generated by the individual's heart, extracting a plurality of characteristics from the bio-potential waveform comprising any of an approximate location of a point of a P peak, an approximate location of a Q-point of a QRS peak system, an approximate location of an R-point of a QRS peak system, an approximate location of an S-point of a QRS peak system, an approximate location of a point of a T peak, using the characteristics to calculate at least one waveform parameter, comparing at least one calculated waveform parameter with at least one previously-acquired waveform parameter to generate a score, and using the score to determine information concerning the identity of the individual.

摘要翻译： 确定关于个体身份的信息的方法，包括测量个体的至少一个生物特征，包括由个人的心脏产生的至少一个生物潜能波形，从生物电位波形中提取多个特征，其包括任何近似值 P峰点的位置，QRS峰值系统的Q点的近似位置，QRS峰值系统的R点的大致位置，QRS峰值系统的S点的大致位置 使用所述特征来计算至少一个波形参数，将至少一个计算的波形参数与至少一个先前获取的波形参数进行比较以产生得分，并且使用所述分数来确定 关于个人身份的信息。

公开(公告)号：US07680604B2

公开(公告)日：2010-03-16

申请号：US11349538

申请日：2006-02-06

申请人： Ronald T. Kurnik

发明人： Ronald T. Kurnik

IPC分类号： G01N33/48 ,  C12P19/34

CPC分类号： G06F19/20 ,  G06F17/10 ,  G06F17/17 ,  G06K9/0053

摘要： Systems and methods for determining the elbow or Ct value in a real-time, or kinetic, PCR amplification curve data set. A PCR data set may be visualized in a two-dimensional plot of fluorescence intensity vs. cycle number. The data set may be adjusted to have a zero slope. In one aspect, a data set is fit to a double sigmoid curve function with the function parameters determined using a Levenberg-Marquardt regression process. The determined parameters are used to subtract off the linear growth portion from the data set to provide a modified data set. For multiple data sets, all the data curves can be aligned in this manner to have a common baseline slope, e.g., a slope of zero. A rotation transform is applied to a modified data set to rotate the data about a defined coordinate such as the origin so that the data point representing the Ct value becomes a minimum or a maximum along the intensity axis. The data point representing the elbow or Ct value of the curve is identified, and this data point is then rotated back and the cycle number of the data point is returned or displayed.

摘要翻译： 用于确定实时或动力学PCR扩增曲线数据集中的弯曲或Ct值的系统和方法。 PCR数据集可以在荧光强度对循环数的二维图中显现。 数据集可以被调整为具有零斜率。 在一个方面，数据集适合于双S形曲线函数，其功能参数使用Levenberg-Marquardt回归过程确定。 确定的参数用于从数据集中减去线性增长部分以提供修改的数据集。 对于多个数据集，所有数据曲线可以以这种方式对齐以具有共同的基线斜率，例如零的斜率。 将旋转变换应用于经修改的数据集以旋转关于诸如原点的定义坐标的数据，使得表示Ct值的数据点沿强度轴成为最小值或最大值。 识别表示曲线的弯曲或Ct值的数据点，然后将该数据点旋转回来，返回或显示数据点的循环编号。

公开(公告)号：US20100036857A1

公开(公告)日：2010-02-11

申请号：US12186496

申请日：2008-08-05

申请人： Mazda A. Marvasti ,  Astghik Grigoryan ,  Arnak Poghosyan ,  Naira Grigoryan ,  Ashot Harutyunyan

发明人： Mazda A. Marvasti ,  Astghik Grigoryan ,  Arnak Poghosyan ,  Naira Grigoryan ,  Ashot Harutyunyan

IPC分类号： G06F17/30

CPC分类号： G06F17/30598 ,  G06K9/0053

摘要： Cycles and other patterns within time-series data are determined. Time-series data are transformed into discretized sets of clustered data that are organized by time period. Comparison is made of the organized data to determine similar time periods and multiclusters of the similar time periods are formed. From the multicluster data, cycles are identified from which thresholds and other useful data may be derived, or the data used for other useful purposes.

公开(公告)号：US07587279B2

公开(公告)日：2009-09-08

申请号：US10886501

申请日：2004-07-06

申请人： Xitong Li ,  Kenneth Stineman

发明人： Xitong Li ,  Kenneth Stineman

IPC分类号： G01N33/48 ,  C12P19/34

CPC分类号： C12Q1/6851 ,  G06K9/0053

摘要： This invention provides a method for the quantitation and quality assurance of QPCR data. In particular, the invention provides a method for extracting data curves from a QPCR assay, estimating the shape and characteristics of an amplification curve and producing a quality score metric. The invention also provides a robust method for calculating a threshold cycle (CT) value and classifying the status of the QPCR results.

摘要翻译： 本发明提供了QPCR数据的定量和质量保证的方法。 特别地，本发明提供了一种从QPCR测定中提取数据曲线的方法，估计扩增曲线的形状和特征并产生质量分数度量。 本发明还提供了用于计算阈值周期（CT）值并对QPCR结果的状态进行分类的鲁棒方法。

公开(公告)号：US07441123B2

公开(公告)日：2008-10-21

申请号：US09815885

申请日：2001-03-23

申请人： J. Spencer Grant ,  Rick V. Murakami ,  Clark Hinton ,  Matthew W. Pettit

发明人： J. Spencer Grant ,  Rick V. Murakami ,  Clark Hinton ,  Matthew W. Pettit

IPC分类号： G06K9/00

CPC分类号： G06K9/0053 ,  A61B5/02416 ,  A61B5/117 ,  G06F21/32 ,  G06K2009/0006 ,  G06K2009/00932 ,  G06K2009/00939 ,  G07C9/00158

摘要： A plurality of electronic signals corresponding to a histological and/or physiological marker, such as a heartbeat, are obtained, from an individual and are converted into electronic signal form. The signals are measured to obtain an actual measurement of a plurality of variable features of the electronic signals relating to the heartbeats. The measurements are mathematically analyzed to provide the probability of divergence of each actual measurement. Using the calculated probability of divergence, subsequent received waveforms measurements are analyzed for authentication purposes.

摘要翻译： 从个体获得对应于组织学和/或生理学标记（例如心跳）的多个电子信号，并将其转换为电子信号形式。 测量信号以获得与心跳相关的电子信号的多个可变特征的实际测量。 在数学上分析测量结果以提供每个实际测量的发散概率。 使用计算的发散概率，分析随后的接收波形测量值以用于认证目的。

公开(公告)号：US07386173B1

公开(公告)日：2008-06-10

申请号：US10649340

申请日：2003-08-27

申请人： Herbert Kaminski ,  Jan-Henner Wurmbach ,  Wolfgang Pusch

发明人： Herbert Kaminski ,  Jan-Henner Wurmbach ,  Wolfgang Pusch

IPC分类号： G06K9/46 ,  G06F3/048

CPC分类号： G06K9/0053 ,  H01J49/0036

摘要： The present invention relates to graphic presentations of complex analytical data strings containing each a multitude of substance-representing peaks (e.g. mass spectra or chromatograms) and pattern recognition or classification techniques in collections of such data strings. The invention proposes to highlight, after execution of the pattern recognition or classification algorithms, the significantly participating peaks in the graphical display so that the nature of these peaks, and the substances represented by these peaks, can easily be further investigated. The content of the graphical display, particularly the peaks, can be interactively accessed by the user and by the pattern recognition programs.

摘要翻译： 本发明涉及在这种数据串的集合中包含各种物质代表峰（例如质谱或色谱图）和模式识别或分类技术的复杂分析数据串的图形呈现。 本发明提出，在执行图案识别或分类算法之后，在图形显示中强调显着参与的峰值，使得可以容易地进一步研究这些峰值的性质以及由这些峰值表示的物质。 图形显示的内容，特别是峰值可以由用户和模式识别程序交互访问。

公开(公告)号：US20070073489A1

公开(公告)日：2007-03-29

申请号：US11241772

申请日：2005-09-29

申请人： Ronald Kurnik

发明人： Ronald Kurnik

IPC分类号： G06F19/00

CPC分类号： G06F17/10 ,  C12Q1/686 ,  G06K9/0053

摘要： Systems and methods for determining the elbow or Ct value in a real-time, or kinetic, PCR amplification curve data set. The PCR data set may be visualized in a two-dimensional plot of fluorescence intensity (y-axis) vs. cycle number (x-axis). The data set is transformed to produce a partition table of data points with one column including the fluorescence at cycle (n) and a second column including the fluorescence at cycle (n+i), where i is typically 1 or greater. A cluster analysis process is applied to the partition table data set to determine a plurality of clusters in the partition table data set. In one aspect, the clustering process used includes a k-means clustering algorithm, where k≧3. The data point representing the elbow or Ct value of the PCR curve is identified as an end point of one of the identified clusters, and the cycle number corresponding to this data point is returned or displayed.

摘要翻译： 用于确定实时或动力学PCR扩增曲线数据集中的弯曲或Ct值的系统和方法。 PCR数据集可以在荧光强度（y轴）与循环数（x轴）的二维图中可视化。 转换数据集以产生具有一列的数据点的分区表，其中包括在循环（n）处的荧光，以及包括循环（n + i）处的荧光的第二列，其中i通常为1或更大。 将分集表分析处理应用于分区表数据集，以确定分区表数据集中的多个集群。 在一个方面，所使用的聚类过程包括k均值聚类算法，其中k> = 3。 表示PCR曲线的弯曲或Ct值的数据点被识别为所识别的一个簇的终点，并且返回或显示与该数据点对应的周期数。