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    FLAVANONES-CONTAINING FOOD COMPOSITIONS
    93.
    发明申请
    FLAVANONES-CONTAINING FOOD COMPOSITIONS 审中-公开
    含有食品的含有食品的组合物

    公开(公告)号：US20120245111A1

    公开(公告)日：2012-09-27

    申请号：US13387409

    申请日：2010-07-22

    Applicant: Pascaline Hoebler

    Inventor： Pascaline Hoebler

    IPC: A61K31/353 ,  A61P17/00 ,  C07H17/07 ,  A61P19/00 ,  C07D311/32 ,  A61K31/7048

    CPC classification number: A61K31/7048 ,  A23C9/152 ,  A23L33/105 ,  A23V2002/00 ,  A23V2250/21164 ,  A23V2200/318 ,  A23V2200/306 ,  A23V2250/2116

    Abstract: The present invention relates to food products comprising flavanones. In particular, it relates to food products comprising hesperidin having improved stability. The present invention also concerns processes for the manufacturing of food products comprising said flavanones, especially hesperidin and to the use of the food products in the manufacture of compositions for the improvement of bone and skin health. Said flavanones are subjected to heating in water to a temperature of at least 138° C.

    Abstract translation: 本发明涉及包含黄烷酮的食品。 特别地，本发明涉及包含具有改善的稳定性的橙皮苷的食品。 本发明还涉及用于制造包含所述黄烷酮，特别是橙皮苷的食品的方法，以及在制备用于改善骨骼和皮肤健康的组合物中使用食品的方法。 将所述黄烷酮在水中加热至至少138℃的温度。

    Novel Flavanone Derivative
    94.
    发明申请
    Novel Flavanone Derivative 有权
    新型黄酮衍生物

    公开(公告)号：US20120202980A1

    公开(公告)日：2012-08-09

    申请号：US13388073

    申请日：2010-07-29

    Applicant: Kenji Sasaki ,  Tomofusa Tsuchiya ,  Abugafar Md. Lokman Hossion ,  Nao Ohtsuka ,  Yoshito Zamami ,  Yuji Kurosaki

    Inventor： Kenji Sasaki ,  Tomofusa Tsuchiya ,  Abugafar Md. Lokman Hossion ,  Nao Ohtsuka ,  Yoshito Zamami ,  Yuji Kurosaki

    IPC: C07H17/07 ,  A61P31/04

    CPC classification number: C07H17/07

    Abstract: Provided is a novel antimicrobial agent. More specifically, provided is a novel antimicrobial agent capable of effectively acting on various resistant bacteria such as VSSA, MRSA, VISA, VRE, and VRSA. A novel flavanone derivative having a six-membered monosaccharide derivative, specifically, a glucose derivative or a galactose derivative is capable of effectively acting on the bacteria. More specifically, a compound represented by the general formula (I) is capable of effectively acting on the bacteria. (In the formula: X represents a six-membered monosaccharide derivative; and Y is substituted by a hydroxyl group.)

    Abstract translation: 提供了一种新型抗菌剂。 更具体地说，提供了能够有效作用于VSSA，MRSA，VISA，VRE，VRSA等各种耐药细菌的新型抗菌剂。 具有六元单糖衍生物，特别是葡萄糖衍生物或半乳糖衍生物的新型黄烷酮衍生物能够有效地作用于细菌。 更具体地，由通式（I）表示的化合物能够有效地作用于细菌。 （式中，X表示六元单糖衍生物，Y表示羟基。）

    Derivatives of genkwanin and sakuranetin, cosmetic and therapeutic use thereof and preparation method of same
    95.
    发明授权
    Derivatives of genkwanin and sakuranetin, cosmetic and therapeutic use thereof and preparation method of same 有权
    genkwanin和sakuranetin的衍生物，其化妆品和治疗用途及其制备方法

    公开(公告)号：US07935672B2

    公开(公告)日：2011-05-03

    申请号：US10598752

    申请日：2005-03-11

    Applicant: Michel Prost ,  Jacqueline Ragot ,  Pierre Tubery

    Inventor： Michel Prost ,  Jacqueline Ragot ,  Pierre Tubery

    IPC: A61K31/7028 ,  A61K31/7042 ,  A61K31/70 ,  C07H17/07

    CPC classification number: A61Q19/00 ,  A61K8/60 ,  A61K31/7016 ,  A61Q19/08

    Abstract: The invention relates to: (i) the use of osyl derivatives of genkwanin and sakuranetin having formula (I) in (a) cosmetics or dermatology and (b) therapeutics; (ii) the use of novel derivatives having formula (I) as industrial products; and (iii) the production method thereof [Formula (I)], wherein symbol [Formula (II)] represents a single or double bond, R represents H or an osyl residue, particularly with structure S1 or s2 [Formula (III)], Z represents H, an alkyl group at C1-C4, acyl at C1-C5, monosaccharide or sulphate.

    Abstract translation: 本发明涉及：（i）在（a）化妆品或皮肤病学和（b）治疗学中使用具有式（I）的genkwanin和sakuranetin的osyl衍生物; （ii）使用具有式（I）的新衍生物作为工业产品; 其中符号[式（Ⅱ）]表示单键或双键，R表示H或者是甲硅烷基，特别是结构S1或s2 [式（I）] [式（I） Z表示H，C1-C4的烷基，C1-C5的酰基，单糖或硫酸根。

    SUPERCOOLING PROMOTING AGENT
    96.
    发明申请
    SUPERCOOLING PROMOTING AGENT 审中-公开
    超级促销代理

    公开(公告)号：US20110078916A1

    公开(公告)日：2011-04-07

    申请号：US12906648

    申请日：2010-10-18

    Applicant: Seizo Fujikawa ,  Jun Kasuga ,  Yasuyuki Hashidoko ,  Keita Arakawa ,  Yukiharu Fukushi

    Inventor： Seizo Fujikawa ,  Jun Kasuga ,  Yasuyuki Hashidoko ,  Keita Arakawa ,  Yukiharu Fukushi

    IPC: F26B5/06 ,  C07H17/07

    CPC classification number: C09K5/10 ,  A01N1/02 ,  A01N1/0221 ,  C07H17/07 ,  C09K5/20 ,  Y10T436/108331

    Abstract: During the investigation of the mechanism that cellular water in woody plants growing in cold districts keeps liquid state at low temperature, the inventors have studied to identify the causative substances. As the results, the present inventors identified supercooling promoting agents in woody plants.The supercooling ability of identified flavonoid glycoside and synthesized flavonoid glycoside with similar structure was tested. It was found that the supercooling promoting agent comprising these flavonoid glycosides enables to stably supercool bulk water at low temperature for long-term. The aqueous solution containing the supercooling promoting agent of the present invention is useful to store biological materials at low temperature.

    Abstract translation: 在研究在寒冷地区生长的木本植物中的细胞水在低温下保持液态的机制时，本发明人已经研究鉴定了致病物质。 结果，本发明人鉴定了木本植物中的过冷促进剂。 测定了确定的类黄酮苷和具有相似结构的合成黄酮苷的过冷能力。 发现包含这些类黄酮苷的过冷促进剂能够在低温下长期稳定地过冷堆积水。 含有本发明的过冷却促进剂的水溶液可用于在低温下储存生物材料。

    Supercooling promoting agent
    98.
    发明授权
    Supercooling promoting agent 有权
    过冷促进剂

    公开(公告)号：US07837895B2

    公开(公告)日：2010-11-23

    申请号：US12309332

    申请日：2007-07-11

    Applicant: Seizo Fujikawa ,  Jun Kasuga ,  Yasuyuki Hashidoko ,  Keita Arakawa ,  Yukiharu Fukushi

    Inventor： Seizo Fujikawa ,  Jun Kasuga ,  Yasuyuki Hashidoko ,  Keita Arakawa ,  Yukiharu Fukushi

    IPC: C09K5/08 ,  C09K3/00 ,  A01N1/02 ,  C07H17/07

    CPC classification number: C09K5/10 ,  A01N1/02 ,  A01N1/0221 ,  C07H17/07 ,  C09K5/20 ,  Y10T436/108331

    Abstract: During the investigation of the mechanism that cellular water in woody plants growing in cold districts keeps liquid state at low temperature, the inventors have studied to identify the causative substances. As the results, the present inventors identified supercooling promoting agents in woody plants. The supercooling ability of identified flavonoid glycoside and synthesized flavonoid glycoside with similar structure was tested. It was found that the supercooling promoting agent comprising these flavonoid glycosides enables to stably supercool bulk water at low temperature for long-term. The aqueous solution containing the supercooling promoting agent of the present invention is useful to store biological materials at low temperature.

    Abstract translation: 在研究在寒冷地区生长的木本植物中的细胞水在低温下保持液态的机制时，本发明人已经研究鉴定了致病物质。 结果，本发明人鉴定了木本植物中的过冷促进剂。 测定了确定的类黄酮苷和具有相似结构的合成黄酮苷的过冷能力。 发现包含这些类黄酮苷的过冷促进剂能够在低温下长期稳定地过冷堆积水。 含有本发明的过冷却促进剂的水溶液可用于在低温下储存生物材料。

    Isoflavone derivatives
    99.
    发明申请
    Isoflavone derivatives 审中-公开

    公开(公告)号：US20060251592A1

    公开(公告)日：2006-11-09

    申请号：US10546470

    申请日：2004-02-18

    Applicant: Sheldon Hendler ,  Jan Zielinski

    Inventor： Sheldon Hendler ,  Jan Zielinski

    IPC: A61K8/49 ,  A61K8/60 ,  C07H17/07

    CPC classification number: A61Q19/08 ,  A61K8/14 ,  A61K8/602 ,  A61K31/353 ,  A61K31/665 ,  A61K31/7048 ,  A61K2800/522 ,  A61Q17/04 ,  C07D311/36

    Abstract: Isoflavones are modified by esterification at one or more of the C4′, C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications produce a carboxylic acid hemiester or a phosphate ester which is biologically hydrolysable. Preferred starting isoflavones are genistin and daidzin, and still more preferably comprises an aglycone form such as genistein or daidzein. Esterified isoflavones may be employed therapeutically or prophylactically for a variety of conditions, provided as a dietary supplement, or added to natural or processed food-stuffs. Further preferred uses include incorporation of contemplated compounds into topical formulations, and especially cosmetic topical formulations.

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