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公开(公告)号：US20100329925A1
公开(公告)日：2010-12-30
申请号：US12656659
申请日：2010-02-12
申请人： Dieter Teppke
发明人： Dieter Teppke
CPC分类号： A61L2/22 , A61L2/186 , A61L2/24 , A61L2202/24
摘要： A device and a method for disinfecting a microtome cryostat with introduction of a disinfection agent (3) into the cryostat chamber (2), action of the disinfection agent on the cryostat chamber, removal of the disinfection agent (3) by precipitation in a colder area (6) and drainage away from there. To enable such a microtome cryostat (1) to be disinfected several times per day without prolonged interruption of operation, a disinfection agent is used (3) that is effective below below 0° C. and is introduced as a mist into the cryostat chamber (2) at below 0° C., the disinfection agent (3) being effective as a hair-frost-like deposit in the cryostat chamber, wherein the hair-frost-like deposit is displaced into a colder area (6) by sublimation and is converted to liquid by sporadic defrosting phases of this area (6) and thus removed.
摘要翻译： 一种将消毒剂（3）引入低温恒温室（2）中消毒切片机低温恒温器的装置和方法，消毒剂在低温恒温室上的作用，通过在较冷的沉淀物中去除消毒剂（3） 区域（6）和排水。 为了使这种切片机低温恒温器（1）每天多次进行消毒而不延长操作中断，使用消毒剂（3），其在低于0℃以下有效，并以雾状引入低温恒温器室（ 2）在低于0℃时，消毒剂（3）在低温恒温器室中作为毛发霜状沉积物有效，其中毛发霜状沉积物通过升华置换到较冷的区域（6）中，并且 通过该区域（6）的散发除霜阶段转化为液体，从而被除去。
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公开(公告)号：US20060219080A1
公开(公告)日：2006-10-05
申请号：US11446237
申请日：2006-06-05
申请人： Hans Heid
发明人： Hans Heid
IPC分类号： B26D1/00
CPC分类号： G01N1/06 , G01N2001/061 , Y10T83/606 , Y10T83/6492 , Y10T83/6508 , Y10T83/8723 , Y10T83/929
摘要： A knife holder for a microtome has a plate arranged pivotably on its base member, which, in its functional position, covers the cutting edge of the knife and is spaced apart from the cutting plane towards the side of the knife holder remote from the specimen. The plate is also spaced apart from the knife holder on the side of the cutting edge of the knife. The plate precludes gripping of the cutting edge of the knife and a pivoting mechanism for the plate is coupled to a switch. When the plate is pivoted out of the functional position, the motor drive of the cutting movement is locked, or a brake precludes any movement of the knife slide or specimen slide. The plate preferably consists of a transparent material to permit observation of section removal in the functional position.
摘要翻译： 用于切片机的刀架具有可枢转地布置在其基部构件上的板，该板在其功能位置上覆盖刀的切割刃，并且与切割平面间隔开远离样品的刀架侧。 该板也与刀架的刀刃切割边一侧间隔开。 该板排除了刀的切割边缘的夹持，并且用于板的枢转机构联接到开关。 当板从功能位置枢转时，切割运动的电机驱动器被锁定，或者制动器阻止刀片或样品滑块的任何运动。 该板优选由透明材料组成，以允许在功能位置观察切除部分。
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3.发明申请公开(公告)号：US20130078669A1
公开(公告)日：2013-03-28
申请号：US13684910
申请日：2012-11-26
发明人： Hans L. Heid , Jose Novoa
IPC分类号： C12Q1/04
CPC分类号： C12Q1/04 , G01N1/06 , G01N1/312 , G01N35/00732 , G01N2035/00148 , G01N2035/00782 , G06F19/00
摘要： The invention relates to a method and device for the cross-referencing of identification (1) of tissue slice supports (2), for microtomised analytical samples still to be mounted thereon, with identification information (3) of a tissue sample holder (4) of a tissue sample (5) which is not yet microtomised. The conventional problem of cross-referencing is improved in a simple manner, whereby the identification information (3) for the tissue sample holder (4) is automatically detected when positioned in the microtome (6) and an identification (1) corresponding thereto is automatically transferred to at least one tissue slice support (2) and that tissue slice support (2), provided with the identification (1), is dispensed for application of the tissue sample slice at the moment when a tissue sample slice must be applied to a tissue slice support (2).
摘要翻译： 本发明涉及一种组织切片支架（2）的识别信息（3）与组织样本支架（4）的识别信息（3）进行交叉参考的方法和装置，用于还有待安装在其上的微量分析样品， 的尚未显微切割的组织样品（5）。 以简单的方式改进了交叉参照的常规问题，由此当定位在切片机（6）中时自动检测组织样本保持器（4）的识别信息（3），并且与其对应的识别符（1）自动地 转移到至少一个组织切片支撑件（2），并且在组织样本切片必须施加于一个组织切片支架（2）的那一刻被分配用于施用组织样本切片的设置有标识（1）的组织切片支架（2） 组织切片支架（2）。
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公开(公告)号：US08246905B2
公开(公告)日：2012-08-21
申请号：US12078580
申请日：2008-04-02
申请人： Dieter Teppke
发明人： Dieter Teppke
摘要： A method for disinfecting a microtome cryostat (1) comprises a defrosting phase (11), provision (13) of a vaporous disinfection agent (2) which acts upon the closed cryostat chamber (3) and a period of time (14) during which said disinfection agent (2) acts, and having an associated device for carrying out the method. According to the invention, fast and effective disinfection and rapid restarting of a microtome cryostat (1) is possible with secure drying, the temperature difference (ΔT1, ΔT2) being produced after the period of time (14) in the cryostat chamber (3) whereupon the precipitated disinfection agent (2) is removed (18) to a cold area.
摘要翻译： 用于消毒切片机低温恒温器（1）的方法包括除霜阶段（11），作用于封闭的低温恒温器室（3）的蒸气消毒剂（2）的提供（13）和一段时间（14），在此期间 所述消毒剂（2）起作用，并具有执行该方法的相关装置。 根据本发明，切片机低温恒温器（1）的快速有效的消毒和快速重新启动是可能的，具有安全的干燥，在低温恒温器中的时间（14）之后产生的温差（＆Dgr; T1，＆Dgr; T2） （3），然后将沉淀的消毒剂（2）除去（18）到冷的区域。
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公开(公告)号：US07964141B2
公开(公告)日：2011-06-21
申请号：US11919763
申请日：2006-03-31
申请人： Hans L. Heid , Stefan Schock
发明人： Hans L. Heid , Stefan Schock
IPC分类号： G01N21/00
CPC分类号： G01N1/312
摘要： The invention relates to an apparatus for handling microtomized tissue samples (1) which are arranged on an object carrier (2) and are provided with a machine-readable code (3), with a reader (4) serving to detect the information of the code (3) and a controller (5) serving to convert the information for handling purposes. In order to use such an apparatus to classify unsorted object carriers (2) with respect to one another in a patient-oriented manner for evaluation purposes, it is proposed that a transfer apparatus (6) and at least one drive (7) are provided, which are formed in such a way that they can pick up object carriers (2) from a supply device (8) and move them to a presentation carrier (9) which has receptacles (10) for a plurality of object carriers (2), an apparatus (11) which is ready to hold presentation carriers (9) being arranged and formed in such a way that it keeps a large number of presentation carriers (9) ready in a manner such that they are accessible to the transfer apparatus (6), wherein the controller (5) is formed in such a way that it controls the at least one drive (7) on the basis of the information of the code (3) of the object carrier (2) to the effect that object carriers (2) which originate from a patient can be moved by the transfer apparatus (6) to at least one presentation carrier (9) in an order which is assigned to the patient.
摘要翻译： 本发明涉及一种用于处理显微组织样本（1）的装置，其被布置在对象载体（2）上并且设置有机器可读代码（3），其中读取器（4）用于检测所述信息 代码（3）和用于转换用于处理目的的信息的控制器（5）。 为了评估目的，为了使用这样一种装置以面向对象的方式相对于彼此分类未排序的对象载体（2），建议设置传送装置（6）和至少一个驱动器（7） ，它们以这样的方式形成，使得它们可以从供应装置（8）拾取物体载体（2）并将它们移动到具有用于多个物体载体（2）的容器（10）的展示承载件（9） 准备好保持呈现载体（9）的装置（11），其被布置和形成，使得它以使得它们可以被传送装置访问的方式保持大量呈现载体（9）准备好 6），其中控制器（5）形成为使得其基于对象载体（2）的代码（3）的信息来控制至少一个驱动器（7），使得该对象 来自患者的载体（2）可以由转移装置（6）移动至至少一个 定位载体（9）以分配给患者的顺序。
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公开(公告)号：US09279745B2
公开(公告)日：2016-03-08
申请号：US14237351
申请日：2012-12-06
发明人： Dieter Teppke
IPC分类号： G01N1/06
CPC分类号： G01N1/06 , Y10S83/9155 , Y10T83/207
摘要： A microtome has a blade holder on which a blade is mounted, an anti-roll device for supporting a section preparation that has been produced by means of the blade, and a suction device by means of which the section preparation can be picked up by suction and carried off. The suction device has a nozzle, with an adjustably mounted nozzle body, and a suction channel. Provision is made that the anti-roll device is mounted on the nozzle body and is adjustable, in particular pivotable, together therewith.
摘要翻译： 切片机具有其上安装有叶片的刀片保持器，用于支撑通过刀片产生的切片准备物的防滚装置，以及抽吸装置，通过该抽吸装置可以通过抽吸拾取部分准备 并带走。 抽吸装置具有喷嘴，具有可调节地安装的喷嘴体和吸入通道。 规定防倾销装置安装在喷嘴主体上并且与其一起可调节，特别是可枢转的。
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7.发明授权Method and devices for the cross-referencing of identification of tissue slice supports for microtomised analytical samples 有权用于微分解分析样品的组织切片支架识别的交叉参考的方法和装置公开(公告)号：US08647836B2
公开(公告)日：2014-02-11
申请号：US13684910
申请日：2012-11-26
发明人： Hans L. Heid , Jose Novoa
CPC分类号： C12Q1/04 , G01N1/06 , G01N1/312 , G01N35/00732 , G01N2035/00148 , G01N2035/00782 , G06F19/00
摘要： The invention relates to a method and device for the cross-referencing of identification (1) of tissue slice supports (2), for microtomised analytical samples still to be mounted thereon, with identification information (3) of a tissue sample holder (4) of a tissue sample (5) which is not yet microtomised. The conventional problem of cross-referencing is improved in a simple manner, whereby the identification information (3) for the tissue sample holder (4) is automatically detected when positioned in the microtome (6) and an identification (1) corresponding thereto is automatically transferred to at least one tissue slice support (2) and that tissue slice support (2), provided with the identification (1), is dispensed for application of the tissue sample slice at the moment when a tissue sample slice must be applied to a tissue slice support (2).
摘要翻译： 本发明涉及一种组织切片支架（2）的识别信息（3）与组织样本支架（4）的识别信息（3）进行交叉参考的方法和装置，用于还有待安装在其上的微量分析样品， 的尚未显微切割的组织样品（5）。 以简单的方式改进了交叉参照的常规问题，由此当定位在切片机（6）中时自动检测组织样本保持器（4）的识别信息（3），并且与其对应的识别符（1）自动地 转移到至少一个组织切片支撑件（2），并且在组织样本切片必须施加于一个组织切片支架（2）的那一刻被分配用于施用组织样本切片的设置有标识（1）的组织切片支撑件（2） 组织切片支架（2）。
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8.发明申请Method and devices for the cross-referencing of identification of tissue slice supports for microtomised analytical samples 有权用于微分解分析样品的组织切片支架识别的交叉参考的方法和装置公开(公告)号：US20080220469A1
公开(公告)日：2008-09-11
申请号：US12149854
申请日：2008-05-09
申请人： Hans L. Heid , Jose Novoa
发明人： Hans L. Heid , Jose Novoa
CPC分类号： C12Q1/04 , G01N1/06 , G01N1/312 , G01N35/00732 , G01N2035/00148 , G01N2035/00782 , G06F19/00
摘要： The invention relates to a method and device for the cross-referencing of identification (1) of tissue slice supports (2), for microtomised analytical samples still to be mounted thereon, with identification information (3) of a tissue sample holder (4) of a tissue sample (5) which is not yet microtomised. The conventional problem of cross-referencing is improved in a simple manner, whereby the identification information (3) for the tissue sample holder (4) is automatically detected when positioned in the microtome (6) and an identification (1) corresponding thereto is automatically transferred to at least one tissue slice support (2) and that tissue slice support (2), provided with the identification (1), is dispensed for application of the tissue sample slice at the moment when a tissue sample slice must be applied to a tissue slice support (2).
摘要翻译： 本发明涉及一种组织切片支架（2）的识别信息（3）与组织样本支架（4）的识别信息（3）进行交叉参考的方法和装置，用于还有待安装在其上的微量分析样品， 的尚未显微切割的组织样品（5）。 以简单的方式改进了交叉参照的常规问题，由此当定位在切片机（6）中时自动检测组织样本保持器（4）的识别信息（3），并且与其对应的识别符（1）自动地 转移到至少一个组织切片支撑件（2），并且在组织样本切片必须施加于一个组织切片支架（2）的那一刻被分配用于施用组织样本切片的设置有标识（1）的组织切片支架（2） 组织切片支架（2）。
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公开(公告)号：US20080181814A1
公开(公告)日：2008-07-31
申请号：US12078580
申请日：2008-04-02
申请人： Dieter TEPPKE
发明人： Dieter TEPPKE
IPC分类号： A61L2/20
摘要： A method for disinfecting a microtome cryostat (1) comprises a defrosting phase (11), provision (13) of a vaporous disinfection agent (2) which acts upon the closed cryostat chamber (3) and a period of time (14) during which said disinfection agent (2) acts, and having an associated device for carrying out the method. According to the invention, fast and effective disinfection and rapid restarting of a microtome cryostat (1) is possible with secure drying, the temperature difference (ΔT1, ΔT2) being produced after the period of time (14) in the cryostat chamber (3) whereupon the precipitated disinfection agent (2) is removed (18) to a cold area.
摘要翻译： 用于消毒切片机低温恒温器（1）的方法包括除霜阶段（11），作用于封闭的低温恒温器室（3）的蒸气消毒剂（2）的提供（13）和一段时间（14），在此期间 所述消毒剂（2）起作用，并具有执行该方法的相关装置。 根据本发明，通过安全干燥，切片机低温恒温器（1）的快速有效的消毒和快速重新启动是可能的，其中温差（DeltaT <1>，ΔT2> 2） 在低温恒温室（3）中经过一段时间（14）后产生沉淀消毒剂（2），并将沉淀的消毒剂（2）除去（18）至寒冷地区。
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公开(公告)号：US07329533B2
公开(公告)日：2008-02-12
申请号：US10495966
申请日：2002-12-11
申请人： Jerry Fredenburgh
发明人： Jerry Fredenburgh
CPC分类号： G01N1/36 , G01N1/31 , Y10T436/25 , Y10T436/2525 , Y10T436/2575
摘要： The invention relates to a unit for the treatment of histological samples. The unit comprises a treatment chamber (1), a device (2) for supplying and removing treatment agents (3, 3′, 3″) to and from the treatment chamber (1), and a control system (4) for the performance of the treatment. The aim of the invention is to develop the unit in such a way that the need to carry out different treatments is taken into account in an economical manner. Towards this end, at least one other treatment chamber (5) is provided, by means of which treatments can be carried out independently from the first treatment chamber (1), the device (2) and the control system (4) also co-operating with that other treatment chamber (5).
摘要翻译： 本发明涉及用于治疗组织学样品的单元。 该单元包括处理室（1），用于向处理室（1）提供和从处理室（1）提供和去除处理剂（3,3'，3“）的装置（2），以及用于 治疗的表现。 本发明的目的是以经济的方式考虑到对进行不同处理的需要的开发单元。 为此，提供了至少一个其它处理室（5），通过该处理室可以独立于第一处理室（1）进行处理，装置（2）和控制系统（4） 与该另一处理室（5）一起操作。
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