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公开(公告)号：US20230414521A1
公开(公告)日：2023-12-28
申请号：US18367416
申请日：2023-09-12
发明人： Susanne Riel
IPC分类号： A61K9/20 , A61K47/26 , A61K47/36 , A61K47/02 , A61K47/38 , A61K47/12 , A61K45/06 , A61K31/165
CPC分类号： A61K9/2054 , A61K9/2018 , A61K9/2095 , A61K47/26 , A61K9/2059 , A61K47/36 , A61K47/02 , A61K9/2013 , A61K9/2009 , A61K47/38 , A61K47/12 , A61K45/06 , A61K31/165
摘要： Pharmaceutical compositions of colchicine for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the compositions of which can be selectively adjusted, respectively, to release the active ingredient along a pre-determined or desired release profile. Methods of treating or preventing cardiovascular disease and/or inflammatory disease in mammalian subjects comprising the administration of the novel formulations disclosed herein are also provided.
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公开(公告)号：US20200030240A1
公开(公告)日：2020-01-30
申请号：US16594543
申请日：2019-10-07
发明人： Susanne Riel
IPC分类号： A61K9/20 , A61K31/165 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/26 , A61K47/36 , A61K47/38
摘要： Pharmaceutical compositions of colchicine for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the compositions of which can be selectively adjusted, respectively, to release the active ingredient along a pre-determined or desired release profile. Methods of treating or preventing cardiovascular disease and/or inflammatory disease in mammalian subjects comprising the administration of the novel formulations disclosed herein are also provided.
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公开(公告)号：US20210361582A1
公开(公告)日：2021-11-25
申请号：US17385734
申请日：2021-07-26
发明人： Susanne Riel
IPC分类号： A61K9/20 , A61K31/165 , A61K31/60 , A61K45/06
摘要： Pharmaceutical compositions of colchicine salicylate, including once-a-day orally administered formulations are provided. Method of treating and/or preventing cardiovascular disease and/or inflammatory disease in mammalian subjects comprising the administration of the novel formulations disclosed herein is also provided.
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公开(公告)号：US11648206B2
公开(公告)日：2023-05-16
申请号：US16594543
申请日：2019-10-07
发明人： Susanne Riel
IPC分类号： A61K31/165 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/26 , A61K47/36 , A61K47/38 , A61K9/20
CPC分类号： A61K9/2054 , A61K9/2009 , A61K9/2013 , A61K9/2018 , A61K9/2059 , A61K9/2095 , A61K31/165 , A61K45/06 , A61K47/02 , A61K47/12 , A61K47/26 , A61K47/36 , A61K47/38
摘要： Pharmaceutical compositions of colchicine for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the compositions of which can be selectively adjusted, respectively, to release the active ingredient along a pre-determined or desired release profile. Methods of treating or preventing cardiovascular disease and/or inflammatory disease in mammalian subjects comprising the administration of the novel formulations disclosed herein are also provided.
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公开(公告)号：US20190054028A1
公开(公告)日：2019-02-21
申请号：US16165696
申请日：2018-10-19
发明人： Susanne Riel
IPC分类号： A61K9/20 , A61K47/38 , A61K47/36 , A61K47/26 , A61K47/12 , A61K47/02 , A61K31/165 , A61K45/06
摘要： Pharmaceutical compositions of colchicine for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the compositions of which can be selectively adjusted, respectively, to release the active ingredient along a pre-determined or desired release profile. Methods of treating or preventing cardiovascular disease and/or inflammatory disease in mammalian subjects comprising the administration of the novel formulations disclosed herein are also provided.
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