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1.发明授权公开(公告)号：US12274532B2
公开(公告)日：2025-04-15
申请号：US17507259
申请日：2021-10-21
Applicant: LightLab Imaging, Inc.
Inventor： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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2.发明授权公开(公告)号：US12138017B2
公开(公告)日：2024-11-12
申请号：US17508502
申请日：2021-10-22
Applicant: LightLab Imaging, Inc.
Inventor： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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3.发明授权公开(公告)号：US12121325B2
公开(公告)日：2024-10-22
申请号：US17508272
申请日：2021-10-22
Applicant: LightLab Imaging, Inc.
Inventor： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
CPC classification number: A61B5/02007 , A61B5/0066 , A61B5/0073 , A61B5/0084
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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4.发明申请公开(公告)号：US20230075598A1
公开(公告)日：2023-03-09
申请号：US17980323
申请日：2022-11-03
Applicant: LightLab Imaging, Inc.
Inventor： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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5.发明申请METHOD AND APPARATUS FOR AUTOMATED DETERMINATION OF A LUMEN CONTOUR OF A STENTED BLOOD VESSEL 审中-公开用于自动测定静脉血液瓶血液的方法和装置公开(公告)号：US20150297373A1
公开(公告)日：2015-10-22
申请号：US14115527
申请日：2013-03-12
Applicant: Lightlab Imaging, Inc.
Inventor： Joseph M. Schmitt , Hiram Bezzerra , Christopher Petroff , Ajay Gopinath
IPC: A61F2/86
CPC classification number: A61F2/86 , A61B5/0066 , A61B5/02007 , A61B5/1076 , A61B2090/061 , A61F2/82 , A61F2230/0069 , A61F2240/001 , A61F2250/006 , G06F19/321
Abstract: In part, the invention relates to a method for sizing a stent for placement in a vessel. In one embodiment, the method includes the steps of: dividing the vessel into a plurality of segments, each segment being defined as the space between branches of the vessel; selecting a starting point that appears to have substantially no disease; defining the diameter at this point to be the maximum diameter; calculating the maximal diameter of the next adjacent segment according to a power law; measuring the actual diameter of the next adjacent segment; selecting either the calculated maximum diameter or the measured maximum diameter depending upon which diameter is larger; using the selected maximum diameter to find the maximum diameter of this next segment; iteratively proceeding until the entire length of the vessel is examined; and selecting a stent in response to the diameters of the end proximal and distal segments.
Abstract translation: 部分地，本发明涉及一种用于定位用于放置在容器中的支架的尺寸的方法。 在一个实施例中，该方法包括以下步骤：将容器分成多个段，每个段被定义为容器的分支之间的空间; 选择似乎没有疾病的起点; 此时将直径定义为最大直径; 根据幂律计算下一相邻段的最大直径; 测量下一个相邻段的实际直径; 选择计算的最大直径或测量的最大直径取决于哪个直径较大; 使用所选择的最大直径来找到该下一段的最大直径; 反复进行，直到检查船舶的整个长度; 以及响应于末端近端和远端段的直径选择支架。
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Patent Agency Ranking
公开(公告)号：US20250082206A1
公开(公告)日：2025-03-13
申请号：US18960195
申请日：2024-11-26
Applicant: LightLab Imaging, Inc.
Inventor： Christopher Petroff , Joseph M. Schmitt
Abstract: In part, the invention relates to methods, apparatus, and systems suitable for determining a fractional flow reserve (FFR) and variations of modifications thereof One embodiment relates to a method and apparatus for obtaining a corrected FFR in a vessel having a stenosis. In one aspect, the invention relates to an apparatus for measuring corrected FFR of a vessel having a stenosis. In one embodiment, the apparatus includes a probe comprising an optical coherence tomography assembly and a pressure assembly; and a processor in communication with the optical coherence tomography assembly and the pressure assembly. In one embodiment, the pressure assembly measures values of pressure in predetermined locations the vessel and communicates them to the processor. In one embodiment, a dual guidewire is used to reduce the interference in the pressure measurement.
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公开(公告)号：US12193789B2
公开(公告)日：2025-01-14
申请号：US16937117
申请日：2020-07-23
Applicant: LightLab Imaging, Inc.
Inventor： Christopher Petroff , Joseph M. Schmitt
Abstract: In part, the invention relates to methods, apparatus, and systems suitable for determining a fractional flow reserve (FFR) and variations of modifications thereof One embodiment relates to a method and apparatus for obtaining a corrected FFR in a vessel having a stenosis. In one aspect, the invention relates to an apparatus for measuring corrected FFR of a vessel having a stenosis. In one embodiment, the apparatus includes a probe comprising an optical coherence tomography assembly and a pressure assembly; and a processor in communication with the optical coherence tomography assembly and the pressure assembly. In one embodiment, the pressure assembly measures values of pressure in predetermined locations the vessel and communicates them to the processor. In one embodiment, a dual guidewire is used to reduce the interference in the pressure measurement.
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公开(公告)号：US11923067B2
公开(公告)日：2024-03-05
申请号：US14115527
申请日：2013-03-12
Applicant: Lightlab Imaging, Inc.
Inventor： Joseph M. Schmitt , Hiram Bezerra , Christopher Petroff , Ajay Gopinath
CPC classification number: G16H30/20 , A61B5/0066 , A61B5/02007 , A61B5/1076 , A61F2/86 , G16H20/40 , A61B2090/061 , A61F2/82 , A61F2230/0069 , A61F2240/001 , A61F2250/006
Abstract: In part, the invention relates to a method for sizing a stent for placement in a vessel. In one embodiment, the method includes the steps of: dividing the vessel into a plurality of segments, each segment being defined as the space between branches of the vessel; selecting a starting point that appears to have substantially no disease; defining the diameter at this point to be the maximum diameter; calculating the maximal diameter of the next adjacent segment according to a power law; measuring the actual diameter of the next adjacent segment; selecting either the calculated maximum diameter or the measured maximum diameter depending upon which diameter is larger; using the selected maximum diameter to find the maximum diameter of this next segment; iteratively proceeding until the entire length of the vessel is examined; and selecting a stent in response to the diameters of the end proximal and distal segments.
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9.发明申请公开(公告)号：US20220095934A1
公开(公告)日：2022-03-31
申请号：US17508272
申请日：2021-10-22
Applicant: LightLab Imaging, Inc.
Inventor： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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10.发明申请公开(公告)号：US20220095933A1
公开(公告)日：2022-03-31
申请号：US17507297
申请日：2021-10-21
Applicant: LightLab Imaging, Inc.
Inventor： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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