公开(公告)号：US20240288399A1

公开(公告)日：2024-08-29

申请号：US18476812

申请日：2023-09-28

Applicant: KOREA ELECTRONICS TECHNOLOGY INSTITUTE

Inventor： Seong Eun KIM ,  Se Eun JEONG ,  Seo Eun LEE

IPC: G01N27/327 ,  G01N27/36 ,  G01N33/543

CPC classification number: G01N27/3278 ,  G01N27/3277 ,  G01N27/36 ,  G01N33/54326 ,  G01N33/5438 ,  G01N2446/20 ,  G01N2446/86

Abstract: Disclosed are a metal nanoparticle-magnetic particle complex, comprising a core comprising a magnetic particle, the first shell comprising metal nanoparticles and formed on the surface of the core, and the second shell comprising a response factor and formed on the surface of the first shell, a method of preparing the complex, and a method of measuring the concentration of a biomarker in a sample using the complex.

公开(公告)号：US20240342725A1

公开(公告)日：2024-10-17

申请号：US18754816

申请日：2024-06-26

Applicant: KOREA ELECTRONICS TECHNOLOGY INSTITUTE

Inventor： Seong Eun KIM ,  Seo Eun LEE

IPC: B01L7/00

CPC classification number: B01L7/00 ,  B01L2200/147 ,  B01L2300/041 ,  B01L2300/1805

Abstract: Proposed are a portable thermal block module, a temperature variable system for a reaction vessel comprising same, and an on-site analysis device comprising same. The portable thermal block module may include a heating element, a thermal block stacked on the heating element, and a fixed unit. The thermal block may include a substrate and one or more bodies. The one or more bodies may be located on the substrate so as to be spaced apart from each other. Each body may include an insertion recess so that at least a portion of a reaction vessel can be inserted therein. The substrate and the bodies may be made of a thermally conductive material.

公开(公告)号：US20240319132A1

公开(公告)日：2024-09-26

申请号：US18511174

申请日：2023-11-16

Applicant: KOREA ELECTRONICS TECHNOLOGY INSTITUTE

Inventor： Seong Eun KIM ,  Se Eun JEONG

IPC: G01N27/327

CPC classification number: G01N27/3276 ,  G01N27/3277

Abstract: Disclosed are a method of manufacturing a working electrode for biosensors, the method including (a) providing a substrate, (b) forming a metal nanostructure on a surface of the substrate, (c) immobilizing a first linker compound on a surface of the metal nanostructure, and (d) binding a response factor to the first linker compound, a working electrode manufactured using the same, a biosensor including the working electrode, and a method of measuring the concentration of a biomarker in a sample using the biosensor.

公开(公告)号：US20230296552A1

公开(公告)日：2023-09-21

申请号：US18321484

申请日：2023-05-22

Applicant: KOREA ELECTRONICS TECHNOLOGY INSTITUTE

Inventor： Seong Eun KIM

IPC: G01N27/327 ,  H01L23/532 ,  H01L21/02

CPC classification number: G01N27/3276 ,  G01N27/3277 ,  G01N27/3278 ,  H01L23/53242 ,  H01L21/02601

Abstract: A method for manufacturing a working electrode for a biosensor is proposed. The method may include providing an Indium Tin Oxide (ITO) glass electrode. The method may also include immobilizing a fixing material on the surface of the ITO glass electrode, wherein the fixing material comprises a first compound and a second compound, and wherein the second compound is a linker compound-metal nanoparticle conjugate. The method may further include immobilizing a reaction factor on the fixing material. An electrode manufactured by the method, and a method for measuring the concentration of biomarkers in a sample using a biosensor including the working electrode are also proposed.