公开(公告)号：US20230090177A1

公开(公告)日：2023-03-23

申请号：US17994638

申请日：2022-11-28

Applicant: GENENTECH, INC.

Inventor： James Thomas Koerber ,  Yonglian Sun

IPC: G01N33/531 ,  G01N33/566 ,  C07K16/18 ,  C07K16/10

Abstract: The present disclosure relates to improved methods and compositions for making extracellular vesicles (EVs). The present disclosure also relates to novel EV-based ELISA assays and kits for performing such assays, as well as methods of producing antibodies to particular antigens using EVs comprising membrane-bound antigen.

公开(公告)号：US20250122280A1

公开(公告)日：2025-04-17

申请号：US18927265

申请日：2024-10-25

Applicant: Genentech, Inc.

Inventor： Nicholas John Agard ,  Thomas Harden Pillow ,  Josefa Dela Cruz Chuh ,  Mary Ann T. Go ,  Katherine R. Kozak ,  Zhonghua Lin ,  Dhaya Seshasayee ,  Shang-Fan Yu ,  James Thomas Koerber ,  Yonglian Sun

IPC: C07K16/28 ,  A61K45/06 ,  A61K47/68 ,  A61K51/10 ,  A61P35/00 ,  G01N33/574 ,  G01N33/68

Abstract: The invention provides anti-Ly6E antibodies and immunoconjugates, and methods of using the same.

公开(公告)号：US20240084042A1

公开(公告)日：2024-03-14

申请号：US18464580

申请日：2023-09-11

Applicant: Genentech, Inc.

Inventor： James Thomas Koerber ,  Wyne Pun Lee ,  Tangsheng Yi ,  Juan Zhang ,  Cary Dean Austin ,  Cecilia Pui Chi Chiu ,  Joseph Edward Chavarria-Smith ,  Jawahar Sudhamsu

IPC: C07K16/46 ,  A61P29/00

CPC classification number: C07K16/468 ,  A61P29/00 ,  C07K2317/14 ,  C07K2317/31 ,  C07K2317/565

Abstract: The invention provides anti-KLK7 antibodies, anti-KLK5 antibodies, anti-KLK5/KLK7 multispecific antibodies, and methods of using the same.

公开(公告)号：US12240910B2

公开(公告)日：2025-03-04

申请号：US17864074

申请日：2022-07-13

Applicant: GENENTECH, INC.

Inventor： Gautham Gampa ,  Iraj Hosseini ,  Mahrukh Huseni ,  James Thomas Koerber ,  Jian Mehr-Dean Payandeh ,  Sascha Rutz ,  Yonglian Sun ,  Cecilia P. C. Chiu ,  Teresita Arenzana Delfino

IPC: C07K16/28 ,  A61K39/00 ,  A61K39/395 ,  A61K45/06 ,  A61P35/00

Abstract: The present disclosure provides anti-CCR8 antibodies, and compositions and methods of their preparation and use.

公开(公告)号：US20210130492A1

公开(公告)日：2021-05-06

申请号：US17024094

申请日：2020-09-17

Applicant: Genentech, Inc.

Inventor： James Thomas Koerber ,  Wyne Pun Lee ,  Tangsheng Yi ,  Juan Zhang ,  Cary Dean Austin ,  Cecilia P.C. Chiu ,  Joseph Chavarria-Smith ,  Jawahar Sudhamsu

IPC: C07K16/40 ,  A61K39/395 ,  A61P17/00

Abstract: The invention provides anti-KLK7 antibodies, anti-KLK5 antibodies, anti-KLK5/KLK7 multispecific antibodies, and methods of using the same.