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公开(公告)号：US11719617B2
公开(公告)日：2023-08-08
申请号：US17519582
申请日：2021-11-05
Applicant: CYTEK BIOSCIENCES, INC.
Inventor： Wenbin Jiang
CPC classification number: G01N15/1436 , G01N15/1434 , G01N15/1459 , G01N21/645 , G01N2015/1006 , G01N2015/1486 , G01N2021/6421
Abstract: A flow-cytometer has an excitation light source generating an excitation light that excites one or more bio-cells in a bio-sample carried by a flow path to luminesce. The flow-cytometer includes a spectrum dispersive element that disperses the luminescent light generated by the bio-sample into a photo-detector array. The flow-cytometer further includes a digital signal processor (DSP) that receives signals from the photo-detector array and generates a self-triggering signal based on the luminescent light generated by the bio-cells in bio-sample. The self-triggering signal triggers data capture in the DSP to improve synchronization with the data generated from signals received from the photo-detector array.
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公开(公告)号：US20220128450A9
公开(公告)日：2022-04-28
申请号：US15942430
申请日：2018-03-30
Applicant: CYTEK BIOSCIENCES, INC.
Inventor： Ming Yan , Yung-Chieh Hsieh , David Vrane , Eric Chase , Wenbin Jiang
Abstract: A system, an apparatus, and a method are provided for a modular flow cytometer with a compact size. In one embodiment, the modular flow cytometry system includes the following: a laser system for emitting laser beams; a flow cell assembly positioned to receive the laser beams at an interrogation region of a fluidics stream where fluoresced cells scatter the laser beams into fluorescent light; a fiber assembly positioned to collect the fluorescent light; and a compact light detection module including a first image array having a transparent block, a plurality of micro-mirrors in a row coupled to a first side of the transparent block, and a plurality of filters in a row coupled to a second side of the transparent block opposite the first side.
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公开(公告)号：US11169075B2
公开(公告)日：2021-11-09
申请号：US14965141
申请日：2015-12-10
Applicant: Cytek Biosciences Inc.
Inventor： Wenbin Jiang
Abstract: A flow-cytometer has an excitation light source generating an excitation light that excites one or more bio-cells in a bio-sample carried by a flow path to luminesce. The flow-cytometer includes a spectrum dispersive element that disperses the luminescent light generated by the bio-sample into a photo-detector array. The flow-cytometer further includes a digital signal processor (DSP) that receives signals from the photo-detector array and generates a self-triggering signal based on the luminescent light generated by the bio-cells in bio-sample. The self-triggering signal triggers data capture in the DSP to improve synchronization with the data generated from signals received from the photo-detector array.
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公开(公告)号：US20220128452A1
公开(公告)日：2022-04-28
申请号：US17519582
申请日：2021-11-05
Applicant: CYTEK BIOSCIENCES, INC.
Inventor： Wenbin Jiang
Abstract: A flow-cytometer has an excitation light source generating an excitation light that excites one or more bio-cells in a bio-sample carried by a flow path to luminesce. The flow-cytometer includes a spectrum dispersive element that disperses the luminescent light generated by the bio-sample into a photo-detector array. The flow-cytometer further includes a digital signal processor (DSP) that receives signals from the photo-detector array and generates a self-triggering signal based on the luminescent light generated by the bio-cells in bio-sample. The self-triggering signal triggers data capture in the DSP to improve synchronization with the data generated from signals received from the photo-detector array.
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公开(公告)号：US11333597B2
公开(公告)日：2022-05-17
申请号：US15942430
申请日：2018-03-30
Applicant: CYTEK BIOSCIENCES, INC.
Inventor： Ming Yan , Yung-Chieh Hsieh , David Vrane , Eric Chase , Wenbin Jiang
IPC: G01N15/14 , G01J3/02 , G01J3/28 , G01J3/36 , G01N21/64 , G01J3/44 , G01J3/18 , G01J3/14 , G01N21/53 , G01J3/12 , G01N15/00 , G01N15/10
Abstract: A system, an apparatus, and a method are provided for a modular flow cytometer with a compact size. In one embodiment, the modular flow cytometry system includes the following: a laser system for emitting laser beams; a flow cell assembly positioned to receive the laser beams at an interrogation region of a fluidics stream where fluoresced cells scatter the laser beams into fluorescent light; a fiber assembly positioned to collect the fluorescent light; and a compact light detection module including a first image array having a transparent block, a plurality of micro-mirrors in a row coupled to a first side of the transparent block, and a plurality of filters in a row coupled to a second side of the transparent block opposite the first side.
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Patent Agency Ranking
公开(公告)号：US20160169809A1
公开(公告)日：2016-06-16
申请号：US14965141
申请日：2015-12-10
Applicant: Cytek Biosciences Inc.
Inventor： Wenbin Jiang
CPC classification number: G01N15/1436 , G01N15/1434 , G01N15/1459 , G01N21/645 , G01N2015/1006 , G01N2015/1486 , G01N2021/6421
Abstract: An optical spectrum analyzer (100) having a an excitation light source (103) with a luminated bio-sample (114) carried by a flow path (102). A spectrum dispersive element 213 dispersants lumineses light generated by the bio-sample (114).
Abstract translation: 具有由流路（102）承载的具有发光的生物样品（114）的激发光源（103）的光谱分析仪（100）。 光谱色散元件213分散剂发光由生物样品（114）产生的光。
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公开(公告)号：US20200333237A1
公开(公告)日：2020-10-22
申请号：US16920618
申请日：2020-07-03
Applicant: CYTEK BIOSCIENCES, INC.
Inventor： David Vrane , Ming Yan , Eric Chase , Wenbin Jiang
Abstract: A system, an apparatus, and a method are provided for a modular flow cytometer with a compact size. In one embodiment, the modular flow cytometry system includes the following: a laser system for emitting laser beams; a flow cell assembly positioned to receive the laser beams at an interrogation region of a fluidics stream where fluoresced cells scatter the laser beams into fluorescent light; a fiber assembly positioned to collect the fluorescent light; and a grating system including a dispersive element and a receiver assembly, wherein the dispersive element is positioned to receive the fluorescent light from the fiber assembly and to direct spectrally dispersed light toward the receiver assembly.
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公开(公告)号：US10739245B2
公开(公告)日：2020-08-11
申请号：US15498397
申请日：2017-04-26
Applicant: CYTEK BIOSCIENCES, INC.
Inventor： David Vrane , Ming Yan , Eric Chase , Wenbin Jiang
Abstract: A system, an apparatus, and a method are provided for a modular flow cytometer with a compact size. In one embodiment, the modular flow cytometry system includes the following: a laser system for emitting laser beams; a flow cell assembly positioned to receive the laser beams at an interrogation region of a fluidics stream where fluoresced cells scatter the laser beams into fluorescent light; a fiber assembly positioned to collect the fluorescent light; and a grating system including a dispersive element and a receiver assembly, wherein the dispersive element is positioned to receive the fluorescent light from the fiber assembly and to direct spectrally dispersed light toward the receiver assembly.
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公开(公告)号：US20240151631A1
公开(公告)日：2024-05-09
申请号：US18231783
申请日：2023-08-08
Applicant: Cytek Biosciences, Inc.
Inventor： Wenbin Jiang
IPC: G01N15/1434 , G01N15/14 , G01N21/64
CPC classification number: G01N15/1436 , G01N15/1434 , G01N15/1459 , G01N21/645 , G01N2015/1006 , G01N2015/1486
Abstract: A method for a flow cytometer includes generating at least one light output with at least one excitation light source; carrying a bio-sample in a medium to a region of a flow path, wherein the bio-sample in the region is illuminated by the at least one light output of the at least one excitation light source to give off luminescence; spatially dispersing a spectrum of the luminescence across photo detection inputs of a photo-detector array; receiving eight or more analog signals from the photo-detector array and converting them to eight or more digital signals respectively; generating a self trigger signal based on the eight or more digital signals and the luminescence; and causing a digital storage space and a digital processing unit to respectively store and analyze the digital data of the eight or more digital signals based on the self trigger signal.
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公开(公告)号：US20180299367A1
公开(公告)日：2018-10-18
申请号：US15942430
申请日：2018-03-30
Applicant: CYTEK BIOSCIENCES, INC.
Inventor： Ming Yan , Yung-Chieh Hsieh , David Vrane , Eric Chase , Wenbin Jiang
Abstract: A system, an apparatus, and a method are provided for a modular flow cytometer with a compact size. In one embodiment, the modular flow cytometry system includes the following: a laser system for emitting laser beams; a flow cell assembly positioned to receive the laser beams at an interrogation region of a fluidics stream where fluoresced cells scatter the laser beams into fluorescent light; a fiber assembly positioned to collect the fluorescent light; and a compact light detection module including a first image array having a transparent block, a plurality of micro-mirrors in a row coupled to a first side of the transparent block, and a plurality of filters in a row coupled to a second side of the transparent block opposite the first side.
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