公开(公告)号：US20250129413A1

公开(公告)日：2025-04-24

申请号：US18983065

申请日：2024-12-16

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Sean CATER ,  Lucas FRENZ ,  Andrew KOHLWAY ,  Jennifer CHEW ,  Rob RAY ,  Ronald LEBOFSKY

IPC: C12Q1/6853 ,  C12N15/10 ,  C12Q1/6806

Abstract: Methods of assessing whether multiple differently-barcodes primers are in partitions are provided.

公开(公告)号：US20190241944A1

公开(公告)日：2019-08-08

申请号：US16260475

申请日：2019-01-29

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Sean CATER ,  Lucas FRENZ ,  Andrew KOHLWAY ,  Jennifer CHEW ,  Rob RAY ,  Ronald LEBOFSKY

IPC: C12Q1/6853 ,  C12N15/10

CPC classification number: C12Q1/6853 ,  C12N15/1065

Abstract: Methods of assessing whether multiple differently-barcodes primers are in partitions are provided.

公开(公告)号：US20240240250A1

公开(公告)日：2024-07-18

申请号：US18431241

申请日：2024-02-02

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Lucas FRENZ ,  Jeremy AGRESTI

IPC: C12Q1/6874 ,  C12Q1/6806

CPC classification number: C12Q1/6874 ,  C12Q1/6806

Abstract: Provided herein are compositions and methods for generating phase-shift barcode oligonucleotides for library construction for next-generation sequencing. In some cases, barcode oligonucleotides are attached to particles or beads. Also provided are methods and kits for using the phase-shift barcode oligonucleotides in sequencing assays.

公开(公告)号：US20210214786A1

公开(公告)日：2021-07-15

申请号：US17215683

申请日：2021-03-29

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Lucas FRENZ ,  Jeremy AGRESTI

IPC: C12Q1/6874 ,  C12Q1/6806

Abstract: Provided herein are compositions and methods for generating phase-shift barcode oligonucleotides for library construction for next-generation sequencing. In some cases, barcode oligonucleotides are attached to particles or beads. Also provided are methods and kits for using the phase-shift barcode oligonucleotides in sequencing assays.

公开(公告)号：US20190126277A1

公开(公告)日：2019-05-02

申请号：US16178300

申请日：2018-11-01

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Lung-Hsin HUNG ,  Robert MELTZER ,  Lucas FRENZ

IPC: B01L3/00 ,  C12Q1/6869

Abstract: Microfluidic systems and methods for arranging a set of objects. In an exemplary method, the set of objects may be transported in carrier fluid along a microfluidic channel structure having a reformatting zone including an object-accessible region and at least one object-excluding region. A portion of the carrier fluid may be moved from the object-accessible region to the at least one object-excluding region in an upstream section of the reformatting zone, to reduce a spacing of objects of the set. The portion of the carrier fluid may be directed into the object-accessible region from the at least one object-excluding region in a downstream section of the reformatting zone, to increase a spacing of objects of the set. The steps of moving and directing in combination may increase the spacing between objects disproportionately for a subset of the objects that are closest to one another.