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公开(公告)号：US20110081668A1
公开(公告)日：2011-04-07
申请号：US12969731
申请日：2010-12-16
申请人： MARY YA-PING YEH , TZU-LING TSENG , CHING-FANG LU , WEI-YA LIN , TSAI-WEI HSU , YI-TING CHEN , CHWEI-SHIUN YANG
发明人： MARY YA-PING YEH , TZU-LING TSENG , CHING-FANG LU , WEI-YA LIN , TSAI-WEI HSU , YI-TING CHEN , CHWEI-SHIUN YANG
CPC分类号： G01N33/6893 , C07K14/70503 , C07K16/2803 , G01N2333/4728 , G01N2333/70503 , G01N2800/347 , G01N2800/52 , G01N2800/56
摘要： Use of urine biomarkers for diagnosing nephropathy, monitoring nephropathy progress, and assessing efficacy of a nephropathy treatment. These urine biomarkers include leukocyte-associated Ig-like receptor-2, alpha-1 acid glycoprotein, their fragments, and combinations thereof.
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公开(公告)号：US20100209948A1
公开(公告)日：2010-08-19
申请号：US12694639
申请日：2010-01-27
申请人： Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ching-Fang Lu , Wei-Ya Lin , Tsai-Wei Hsu , Yi-Ting Chen , Chwei-Shiun Yang
发明人： Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ching-Fang Lu , Wei-Ya Lin , Tsai-Wei Hsu , Yi-Ting Chen , Chwei-Shiun Yang
IPC分类号： G01N33/53
CPC分类号： G01N33/6893 , C07K14/70503 , C07K16/2803 , G01N2333/4728 , G01N2333/70503 , G01N2800/347 , G01N2800/52 , G01N2800/56
摘要： Use of urine biomarkers for diagnosing nephropathy, monitoring nephropathy progress, and assessing efficacy of a nephropathy treatment. These urine biomarkers include leukocyte-associated Ig-like receptor-2, alpha-1 acid glycoprotein, their fragments, and combinations thereof.
摘要翻译： 使用尿生物标志物诊断肾病，监测肾病进展，并评估肾病治疗的疗效。 这些尿生物标志物包括白细胞相关的Ig样受体-2，α-1酸性糖蛋白，其片段及其组合。
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公开(公告)号：US20100197033A1
公开(公告)日：2010-08-05
申请号：US12694575
申请日：2010-01-27
申请人： Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
发明人： Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
IPC分类号： G01N33/48
CPC分类号： G01N33/6893 , G01N2333/4728 , G01N2333/52 , G01N2333/71 , G01N2333/8125 , G01N2800/347 , G01N2800/52 , G01N2800/56
摘要： Use of urine and serum biomarkers in diagnosing diabetic nephropathy, staging diabetic nephropathy, monitoring diabetic nephropathy progress, and assessing efficacy of diabetic nephropathy treatments. These biomarkers include urine precursor alpha-2-HS-glycoprotein, urine alpha-1 antitrypsin, urine alpha-1 acid glycoprotein, urine osteopontin, serum osteopontin, their fragments, and combinations thereof.
摘要翻译： 使用尿液和血清生物标志物诊断糖尿病肾病，分期糖尿病肾病，监测糖尿病肾病进展，评估糖尿病肾病治疗效果。 这些生物标志物包括尿前体α-2-HS-糖蛋白，尿α-1抗胰蛋白酶，尿α-1酸糖蛋白，尿骨桥蛋白，血清骨桥蛋白，其片段及其组合。
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公开(公告)号：US08476077B2
公开(公告)日：2013-07-02
申请号：US12969039
申请日：2010-12-15
申请人： Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
发明人： Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
CPC分类号： G01N33/6893 , G01N2333/4728 , G01N2333/52 , G01N2333/71 , G01N2333/8125 , G01N2800/347 , G01N2800/52 , G01N2800/56
摘要： Disclosed is use of urine and serum biomarkers in diagnosing diabetic nephropathy, staging diabetic nephropathy, monitoring diabetic nephropathy progress, and assessing efficacy of diabetic nephropathy treatments. These biomarkers include urine precursor alpha-2-HS-glycoprotein, urine alpha-1 antitrypsin, urine alpha-1 acid glycoprotein, urine osteopontin, serum osteopontin, their fragments, and combinations thereof.
摘要翻译： 公开了使用尿液和血清生物标志物诊断糖尿病肾病，分期糖尿病肾病，监测糖尿病肾病进展和评估糖尿病肾病治疗效果。 这些生物标志物包括尿前体α-2-HS-糖蛋白，尿α-1抗胰蛋白酶，尿α-1酸糖蛋白，尿骨桥蛋白，血清骨桥蛋白，其片段及其组合。
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公开(公告)号：US20110086372A1
公开(公告)日：2011-04-14
申请号：US12973018
申请日：2010-12-20
申请人： Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ching-Fang Lu , Wei-Ya Lin , Tsai-Wei Hsu , Yi-Ting Chen , Chwei-Shiun Yang
发明人： Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ching-Fang Lu , Wei-Ya Lin , Tsai-Wei Hsu , Yi-Ting Chen , Chwei-Shiun Yang
CPC分类号： G01N33/6893 , C07K14/70503 , C07K16/2803 , G01N2333/4728 , G01N2333/70503 , G01N2800/347 , G01N2800/52 , G01N2800/56
摘要： Use of urine biomarkers for diagnosing nephropathy, monitoring nephropathy progress, and assessing efficacy of a nephropathy treatment. These urine biomarkers include leukocyte-associated Ig-like receptor-2, alpha-1 acid glycoprotein, their fragments, and combinations thereof.
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公开(公告)号：US20110081667A1
公开(公告)日：2011-04-07
申请号：US12968841
申请日：2010-12-15
申请人： Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ching-Fang Lu , Wei-Ya Lin , Tsai-Wei Hsu , Yi-Ting Chen , Chwei-Shiun Yang
发明人： Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ching-Fang Lu , Wei-Ya Lin , Tsai-Wei Hsu , Yi-Ting Chen , Chwei-Shiun Yang
CPC分类号： G01N33/6893 , C07K14/70503 , C07K16/2803 , G01N2333/4728 , G01N2333/70503 , G01N2800/347 , G01N2800/52 , G01N2800/56
摘要： Use of urine biomarkers for diagnosing nephropathy, monitoring nephropathy progress, and assessing efficacy of a nephropathy treatment. These urine biomarkers include leukocyte-associated Ig-like receptor-2, alpha-1 acid glycoprotein, their fragments, and combinations thereof.
摘要翻译： 使用尿生物标志物诊断肾病，监测肾病进展，并评估肾病治疗的疗效。 这些尿生物标志物包括白细胞相关的Ig样受体-2，α-1酸性糖蛋白，其片段及其组合。
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公开(公告)号：US20100136579A1
公开(公告)日：2010-06-03
申请号：US12628758
申请日：2009-12-01
申请人： Tzu-Ling Tseng , Hung-Yi Li , Yen-Peng Li , Angelina Huai-Lo Lee , Yi-Chen Liu , Ping-Fu Cheng , Wei-Ya Lin , Hong-Zen Yeh
发明人： Tzu-Ling Tseng , Hung-Yi Li , Yen-Peng Li , Angelina Huai-Lo Lee , Yi-Chen Liu , Ping-Fu Cheng , Wei-Ya Lin , Hong-Zen Yeh
IPC分类号： G01N33/573 , C12Q1/52 , C12Q1/37
CPC分类号： G01N33/6893 , G01N33/487 , G01N33/49 , G01N33/50 , G01N33/5067 , G01N33/53 , G01N33/576 , G01N2333/70539 , G01N2333/96494 , G01N2333/9723 , G01N2800/085
摘要： Identification of urokinase-type plasminogen, matrix metalloproteinase 9, and β-2-microglobulin as novel biomarkers associated with liver fibrosis and uses thereof in diagnosing liver fibrosis.
摘要翻译： 鉴定尿激酶型纤溶酶原，基质金属蛋白酶9和＆bgr.2-微球蛋白作为与肝纤维化相关的新型生物标志物及其在诊断肝纤维化中的用途。
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公开(公告)号：US08470547B2
公开(公告)日：2013-06-25
申请号：US12969731
申请日：2010-12-16
申请人： Tzu-Ling Tseng , Ching-Fang Lu , Wei-Ya Lin , Tsai-Wei Hsu , Mary Ya-Ping Yeh , Yi-Ting Chen , Chwei-Shiun Yang
发明人： Tzu-Ling Tseng , Ching-Fang Lu , Wei-Ya Lin , Tsai-Wei Hsu , Mary Ya-Ping Yeh , Yi-Ting Chen , Chwei-Shiun Yang
CPC分类号： G01N33/6893 , C07K14/70503 , C07K16/2803 , G01N2333/4728 , G01N2333/70503 , G01N2800/347 , G01N2800/52 , G01N2800/56
摘要： Use of urine biomarkers for diagnosing nephropathy, monitoring nephropathy progress, and assessing efficacy of a nephropathy treatment. These urine biomarkers include leukocyte-associated Ig-like receptor-2, alpha-1 acid glycoprotein, their fragments, and combinations thereof.
摘要翻译： 使用尿生物标志物诊断肾病，监测肾病进展，并评估肾病治疗的疗效。 这些尿生物标志物包括白细胞相关的Ig样受体-2，α-1酸性糖蛋白，其片段及其组合。
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公开(公告)号：US08465980B2
公开(公告)日：2013-06-18
申请号：US12694575
申请日：2010-01-27
申请人： Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
发明人： Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
CPC分类号： G01N33/6893 , G01N2333/4728 , G01N2333/52 , G01N2333/71 , G01N2333/8125 , G01N2800/347 , G01N2800/52 , G01N2800/56
摘要： Disclosed is use of urine and serum biomarkers in diagnosing diabetic nephropathy, staging diabetic nephropathy, monitoring diabetic nephropathy progress, and assessing efficacy of diabetic nephropathy treatments. These biomarkers include urine precursor alpha-2-HS-glycoprotein, urine alpha-1 antitrypsin, urine alpha-1 acid glycoprotein, urine osteopontin, serum osteopontin, their fragments, and combinations thereof.
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公开(公告)号：US20110086371A1
公开(公告)日：2011-04-14
申请号：US12972936
申请日：2010-12-20
申请人： Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
发明人： Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
IPC分类号： G01N33/53 , C07K16/18 , G01N33/566
CPC分类号： G01N33/6893 , G01N2333/4728 , G01N2333/52 , G01N2333/71 , G01N2333/8125 , G01N2800/347 , G01N2800/52 , G01N2800/56
摘要： Use of urine and serum biomarkers in diagnosing diabetic nephropathy, staging diabetic nephropathy, monitoring diabetic nephropathy progress, and assessing efficacy of diabetic nephropathy treatments. These biomarkers include urine precursor alpha-2-HS-glycoprotein, urine alpha-1 antitrypsin, urine alpha-1 acid glycoprotein, urine osteopontin, serum osteopontin, their fragments, and combinations thereof.
摘要翻译： 使用尿液和血清生物标志物诊断糖尿病肾病，分期糖尿病肾病，监测糖尿病肾病进展，评估糖尿病肾病治疗效果。 这些生物标志物包括尿前体α-2-HS-糖蛋白，尿α-1抗胰蛋白酶，尿α-1酸糖蛋白，尿骨桥蛋白，血清骨桥蛋白，其片段及其组合。
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