- 专利标题： Compositions and methods for the construction of a random allelic series
-
申请号： US15146621申请日： 2016-05-04
-
公开(公告)号： US09868947B2公开(公告)日： 2018-01-16
- 发明人: Christine Gurnett , Gabriel Haller , Matthew Dobbs , David Alvarado
- 申请人： Washington University
- 申请人地址： US MO St. Louis US FL Tampa
- 专利权人： WASHINGTON UNIVERSITY,SHRINERS HOSPITALS FOR CHILDREN
- 当前专利权人： WASHINGTON UNIVERSITY,SHRINERS HOSPITALS FOR CHILDREN
- 当前专利权人地址： US MO St. Louis US FL Tampa
- 代理机构： Polsinelli PC
- 主分类号： C12P19/40
- IPC分类号： C12P19/40 ; C12N15/10
摘要：
The present disclosure provides a method of making a systematic single point mutation in a target nucleic acid and a method of generating a mutational library comprising target nucleic acids with single point mutations. The mutational library comprises target nucleic acids with single point mutations distributed evenly throughout the target nucleic acid.
公开/授权文献
信息查询
