A display panel comprising a first substrate and a second substrate cell-assembled with the first substrate, wherein the first substrate is provided with at least one annular protrusion made of frit with the same center point, and the second substrate is provided with an encapsulating zone to fit the annular protrusion, the encapsulating zone comprising at least one annular groove, the amount of which is less than or equal to that of the annular protrusion(s). Embodiments of the present disclosure further provide a packaging method and a display device. An OLED display panel can be ensured to have good internal sealing property by means of its package, and its service life is prolonged.