Invention Grant
- Patent Title: Deoxycytidine kinase binding compounds
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Application No.: US14002964Application Date: 2012-03-08
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Publication No.: US09688673B2Publication Date: 2017-06-27
- Inventor: Caius G. Radu , Hsiang-I Liao , Nagichettiar Satyamurthy , Johannes Czernin , Jennifer M. Murphy , David A. Nathanson
- Applicant: Caius G. Radu , Hsiang-I Liao , Nagichettiar Satyamurthy , Johannes Czernin , Jennifer M. Murphy , David A. Nathanson
- Applicant Address: US CA Oakland
- Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Oakland
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- International Application: PCT/US2012/028259 WO 20120308
- International Announcement: WO2012/122368 WO 20120913
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14 ; C07D417/12 ; C07D417/14 ; A61K31/426 ; A61K31/44 ; A61K31/506 ; A61K31/513 ; G01N33/50
Abstract:
The invention provides compounds that bind to deoxycytidine kinase (dCK) and compositions including pharmaceutically acceptable compositions containing the compounds. The compounds are useful in treating diseases and disorders where dCK activity is implicated such as cancer and immune disorders. The compounds also find use in clinical methodologies including positron emission tomography (PET) imaging.
Public/Granted literature
- US20130336883A1 DEOXYCYTIDINE KINASE BINDING COMPOUNDS Public/Granted day:2013-12-19
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