发明授权
- 专利标题： Viruses associated with immunodeficiency and enteropathy and methods using same
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申请号： US14429559申请日： 2013-09-19
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公开(公告)号： US09683268B2公开(公告)日： 2017-06-20
- 发明人: Dan Barouch , Herbert W Virgin , David Wang , Guoyan Zhao , Larissa Thackray , Scott Handley , Rachel Presti
- 申请人： BETH ISRAEL DEACONESS MEDICAL CENTER, INC. , WASHINGTON UNIVERSITY
- 申请人地址： US MA Boston US MO Saint Louis
- 专利权人： Beth Israel Deaconess,Washington University
- 当前专利权人： Beth Israel Deaconess,Washington University
- 当前专利权人地址： US MA Boston US MO Saint Louis
- 代理机构： Zackson Law LLC
- 代理商 Saul L. Zackson
- 国际申请： PCT/US2013/060579 WO 20130919
- 国际公布： WO2014/047261 WO 20140327
- 主分类号： C12Q1/70
- IPC分类号： C12Q1/70 ; A61K39/235 ; A61K39/21 ; C12N7/00 ; A61K39/00
摘要：
The present invention relates to previously undescribed viruses that are associated with significant expansion of the virome, immunodeficiency, and enteropathy during lentiviral infection. The invention also provides methods to detect acquired immune deficiency syndrome (AIDS) or AIDS progression in a subject, methods to diagnose immunodeficiency or enteropathy in a subject, and methods to identify a therapeutic agent to treat the same.
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