Invention Grant
- Patent Title: Data analysis of impedance-based cardiomyocyte-beating signals as detected on real-time cell analysis (RTCA) cardio instruments
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Application No.: US13109809Application Date: 2011-05-17
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Publication No.: US09612234B2Publication Date: 2017-04-04
- Inventor: Nan Li , Xiaobo Wang , Yama A. Abassi , Biao Xi , Wen Fu Zhang , Xiao Xu
- Applicant: Nan Li , Xiaobo Wang , Yama A. Abassi , Biao Xi , Wen Fu Zhang , Xiao Xu
- Applicant Address: US CA San Diego
- Assignee: ACEA Biosciences, Inc.
- Current Assignee: ACEA Biosciences, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Wagenknecht IP Law Group PC
- Main IPC: C40B30/06
- IPC: C40B30/06 ; G01N7/00 ; C12Q1/00 ; G01N33/50 ; G01N33/483
Abstract:
A method of determining one or more beating parameters for use in cardiomyocyte beating analysis including: providing a cell analysis device including wells, each well including a sensor capable of monitoring beating of cardiomyoctes in millisecond time resolution; adding cardiomyocytes to the wells; monitoring the beating of the cardiomyocytes in millisecond time resolution to obtain a plurality of beating measurements; and calculating one or more beating parameters from the plurality of beating measurements.
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