A method and system for operating a brake system for motor vehicles, including a plurality of wheel brakes for which wheel-individual nominal pressure includes an electrically controllable pressure supply device, to provide a brake system pressure for actuating the wheel brakes. The brake system pressure provided by the pressure supply device can be determined. An electrically controllable inlet valve and electrically controllable outlet valve per wheel brake adjust wheel-individual brake pressures. At least one outlet valve is analogized for analog-controlled and is controlled by an electric control variable, wherein at least one valve-specific control characteristic and/or a valve-specific parameter is determined for the analogized or analog-controlled outlet valve by the brake system, and wherein the analogized or analog-controlled outlet valve is controlled as a function of the valve-specific control characteristic and/or the valve-specific parameter for the degradation of the brake pressure in the wheel brake associated with the outlet valve.