发明授权
US09475866B2 Human islet amyloid polypeptide (hIAPP) specific antibodies and uses thereof
有权
人胰岛淀粉样蛋白多肽（hIAPP）特异性抗体及其用途
- 专利标题： Human islet amyloid polypeptide (hIAPP) specific antibodies and uses thereof
- 专利标题（中）： 人胰岛淀粉样蛋白多肽（hIAPP）特异性抗体及其用途
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申请号： US14427575申请日： 2013-09-12
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公开(公告)号： US09475866B2公开(公告)日： 2016-10-25
- 发明人: Jan Grimm , Fabrice Heitz , Feng Chen , Ioana Combaluzier
- 申请人： Neurimmune Holding AG
- 申请人地址： CH Schlieren
- 专利权人： Neurimmune Holding AG
- 当前专利权人： Neurimmune Holding AG
- 当前专利权人地址： CH Schlieren
- 代理机构： Clark & Elbing LLP
- 代理商 Kristina Bieker-Brady
- 优先权： EP12184134 20120912
- 国际申请： PCT/EP2013/068907 WO 20130912
- 国际公布： WO2014/041069 WO 20140320
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C07K16/18 ; C12N15/63 ; G01N33/68 ; G01N33/577 ; C07K14/47 ; C07K7/06 ; G01N33/543 ; A61K39/00
摘要：
Provided are novel human islet amyloid polypeptide, also known as amylin and IAPP and proIAPP respectively, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for IAPP and/or proIAPP are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for IAPP and/or proIAPP targeted immunotherapy and diagnostics, respectively.
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