- 专利标题: Inhibitors of the influenza A virus M2 proton channel
-
申请号: US14036813申请日: 2013-09-25
-
公开(公告)号: US09403777B2公开(公告)日: 2016-08-02
- 发明人: William F. DeGrado , Jun Wang
- 申请人: The Trustees Of The University Of Pennsylvania
- 申请人地址: US PA Philadelphia
- 专利权人: The Trustees of the University of Pennsylvania
- 当前专利权人: The Trustees of the University of Pennsylvania
- 当前专利权人地址: US PA Philadelphia
- 代理机构: Baker & Hostetler LLP
- 主分类号: C07C255/47
- IPC分类号: C07C255/47 ; C07C61/13 ; C07C211/38 ; C07D223/32 ; C07C49/447 ; C07C49/427 ; A61K31/045 ; A61K31/122 ; A61K31/13 ; A61K31/19 ; A61K31/277 ; A61K31/55 ; C07C35/23 ; C07C49/323 ; C07C49/623 ; C07C211/19
摘要:
Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza A-affected disease state or infection comprising administering a composition comprising one or more compounds that have been identified as being capable of interaction with the M2 protein.
公开/授权文献
- US20140024635A1 INHIBITORS OF THE INFLUENZA A VIRUS M2 PROTON CHANNEL 公开/授权日:2014-01-23
信息查询