Invention Grant
US09399787B2 Real-time electronic cell sensing system and applications for cytotoxicity profiling and compound assays
有权
实时电子细胞感测系统及其细胞毒性分析和化合物分析的应用
- Patent Title: Real-time electronic cell sensing system and applications for cytotoxicity profiling and compound assays
- Patent Title (中): 实时电子细胞感测系统及其细胞毒性分析和化合物分析的应用
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Application No.: US13720124Application Date: 2012-12-19
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Publication No.: US09399787B2Publication Date: 2016-07-26
- Inventor: Yama A. Abassi , Xiaobo Wang , Xiao Xu
- Applicant: ACEA BIOSCIENCES, INC
- Applicant Address: US CA San Diego
- Assignee: ACEA Biosciences, Inc.
- Current Assignee: ACEA Biosciences, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Wagenknecht IP Law Group, PC
- Main IPC: G01R27/08
- IPC: G01R27/08 ; C12Q1/00 ; C12Q1/70 ; C12Q1/02 ; G01N27/02 ; G01N33/50 ; G01N33/543 ; G01N33/483
Abstract:
A method of performing an assay of a response of two or more cell types to a test compound, including: providing a device for monitoring cell-substrate impedance, adding at least two different cell types to the device; adding at least one test compound to form at least two test compound wells; providing at least two control wells; monitoring impedance of the at least two test compound wells and of the at least two control wells at three or more time points after adding the at least one test compound; and analyzing measured impedance from the at least two test compound wells and from the at least two control wells at the three or more time points to obtain information on the response of the different cell types to the at least one test compound.
Public/Granted literature
- US20130123136A1 REAL-TIME ELECTRONIC CELL SENSING SYSTEM AND APPLICATIONS FOR CYTOTOXICITY PROFILING AND COMPOUND ASSAYS Public/Granted day:2013-05-16
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