A memory system is provided including a host configured to generate data bit inversion (DBI) information of data according to a major bit of the data, and a nonvolatile memory device configured to invert one or more bits of the data according to the DBI information, and to program the DBI information and the data. A control method of a memory system comprises generating DBI information according to the number of “1” bits of data relative to the number of “0” bits of the data, transferring the data and the DBI information, and inverting bits of the data according to the DBI information, the inverted bits of the data being programmed at the nonvolatile memory device.