发明授权
US08788215B2 Methods of associating an unknown biological specimen with a family
有权
将未知生物标本与家族联系起来的方法
- 专利标题： Methods of associating an unknown biological specimen with a family
- 专利标题（中）： 将未知生物标本与家族联系起来的方法
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申请号： US13621311申请日： 2012-09-17
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公开(公告)号： US08788215B2公开(公告)日： 2014-07-22
- 发明人: Ranajit Chakraborty , John Douglas Birdwell , Tse-Wei Wang , Dale V. Stansberry
- 申请人： The University of Tennessee Research Foundation
- 申请人地址： US TN Knoxville
- 专利权人： University of Tennessee Research Foundation
- 当前专利权人： University of Tennessee Research Foundation
- 当前专利权人地址： US TN Knoxville
- 代理机构： Cameron LLP
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; G06F19/18
摘要：
The present invention provides a method of predicting whether an unknown biological specimen originates from a member of a particular family. The method compares DNA profiles from at least one unknown biological specimen to DNA profiles of more than one family member, which significantly increases the methods' predictive ability. In particular, the invention describes a method of comparing test DNA profiles from unknown biological specimens to a family pedigree comprising target DNA profiles obtained from biological specimens of family members. In one embodiment, a modified Elston Stewart algorithm is used to determine a probability that a genetic relationship exists between at least one unknown biological specimen and the family pedigree.
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