Invention Grant
- Patent Title: AKT protein kinase inhibitors
- Patent Title (中): AKT蛋白激酶抑制剂
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Application No.: US12567258Application Date: 2009-09-25
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Publication No.: US08680114B2Publication Date: 2014-03-25
- Inventor: Ian S. Mitchell , Keith L. Spencer , Peter Stengel , Yongxin Han , Nicholas C. Kallan , Mark Munson , Guy P. A. Vigers , James Blake , Anthony Piscopio , John Josey , Scott Miller , Dengming Xiao , Rui Xu , Chang Rao , Bing Wang , April L. Bernacki
- Applicant: Ian S. Mitchell , Keith L. Spencer , Peter Stengel , Yongxin Han , Nicholas C. Kallan , Mark Munson , Guy P. A. Vigers , James Blake , Anthony Piscopio , John Josey , Scott Miller , Dengming Xiao , Rui Xu , Chang Rao , Bing Wang , April L. Bernacki
- Applicant Address: US CO Boulder US CA South San Francisco
- Assignee: Array Biopharma, Inc.,Genentech, Inc.
- Current Assignee: Array Biopharma, Inc.,Genentech, Inc.
- Current Assignee Address: US CO Boulder US CA South San Francisco
- Agency: Viksnins Harris & Padys PLLP
- Main IPC: A61K31/47
- IPC: A61K31/47 ; A01N43/42 ; C07D215/00
Abstract:
The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
Public/Granted literature
- US20100168123A1 AKT PROTEIN KINASE INHIBITORS Public/Granted day:2010-07-01
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