Invention Grant
- Patent Title: Immobilization of membrane proteins onto supports via an amphiphile
- Patent Title (中): 通过两亲物将膜蛋白固定在载体上
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Application No.: US13479890Application Date: 2012-05-24
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Publication No.: US08674044B2Publication Date: 2014-03-18
- Inventor: Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
- Applicant: Jean-Luc Popot , Delphine Charvolin , Fabrice Giusti
- Applicant Address: FR Paris
- Assignee: Centre National de la Recherche Scientifique (CNRS)
- Current Assignee: Centre National de la Recherche Scientifique (CNRS)
- Current Assignee Address: FR Paris
- Agency: Pepper Hamilton LLP
- Priority: FR0609882 20061113
- Main IPC: A61K47/48
- IPC: A61K47/48 ; C08G63/48 ; C08G63/91 ; C08L89/00 ; D21H19/50 ; C08F20/00 ; C08F22/38 ; C08F26/00 ; C08F120/00 ; C08F220/54 ; C08F220/70 ; C08F222/38 ; C08F226/02 ; C08F236/00 ; C12Q1/00

Abstract:
The invention pertains to the field of membrane protein immobilization onto supports. It relates to a product comprising a support and at least one membrane protein attached to the surface thereof, characterized in that said membrane protein is attached to said support using an amphiphilic molecule with which said membrane protein is complexed. It also relates to a process for preparing such product, as well as to various applications in the fields of diagnosis, drug design and biotechnologies. It further relates to a kit, together with a functionalized amphiphilic molecule, for preparing a product according to the invention comprising a support and an amphiphilic molecule, wherein the amphiphilic molecule and the support interact through a hydrophobic bond, an ionic bond, a specific bond or a covalent bond.
Public/Granted literature
- US20130023026A1 IMMOBILIZATION OF MEMBRANE PROTEINS ONTO SUPPORTS VIA AN AMPHIPHILE Public/Granted day:2013-01-24
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