发明授权
- 专利标题： Controlled release micro-capsule for osteogenic action
- 专利标题（中）： 用于成骨作用的控释微胶囊
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申请号： US13203603申请日： 2010-02-26
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公开(公告)号： US08496964B2公开(公告)日： 2013-07-30
- 发明人: Prabhat Ranjan Mishra , Ritu Trivedi , Girish Kumar Gupta , Avinash Kumar , Varsha Gupta , Srikanta Kumar Rath , Kamini Srivastava , Naibedya Chattopadhyay , Anil Kumar Dwivedi
- 申请人： Prabhat Ranjan Mishra , Ritu Trivedi , Girish Kumar Gupta , Avinash Kumar , Varsha Gupta , Srikanta Kumar Rath , Kamini Srivastava , Naibedya Chattopadhyay , Anil Kumar Dwivedi
- 申请人地址： IN New Delhi
- 专利权人： Council of Scientific & Industrial Research
- 当前专利权人： Council of Scientific & Industrial Research
- 当前专利权人地址： IN New Delhi
- 代理机构： Abelman, Frayne & Schwab
- 优先权： IN384/DEL/2009 20090227
- 国际申请： PCT/IN2010/000115 WO 20100226
- 国际公布： WO2010/097814 WO 20100902
- 主分类号： A61K9/52
- IPC分类号： A61K9/52 ; A61K9/50 ; A61K31/70 ; B01J13/00 ; B05D3/00 ; A01N43/04
摘要：
The present invention relates to a microcapsule for controlled release of flavanoid compound and a process for preparation thereof. The microcapsule comprising a core particle consisting of a calcium salt, Pluronic F68 [poly (ethylene oxide-co-polypropylene oxide), block poly oxyethylene-polypropylene block copolymer], loaded with a flavanoid compound, the resulting core particle having a plurality of alternate layers of cationic and anionic polyelectrolytes adsorbed thereon and an outer layer formed by a bile salt, wherein the flavanoid is ranging between 10 to 96% by weight.
公开/授权文献
- US20110305754A1 CONTROLLED RELEASE MICRO-CAPSULE FOR OSTEOGENIC ACTION 公开/授权日：2011-12-15
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