Invention Grant
- Patent Title: Quinolone neuropeptide S receptor antagonists
- Patent Title (中): 喹诺酮神经肽S受体拮抗剂
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Application No.: US13127898Application Date: 2009-11-03
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Publication No.: US08389720B2Publication Date: 2013-03-05
- Inventor: James C. Barrow , Mark T. Bilodeau , Christopher D. Cox , John C. Hartnett , Nathan R. Kett , Yiwei Li , Peter J. Manley , Jeffrey Melamed , William D. Shipe , B. Wesley Trotter , Amy Zartman
- Applicant: James C. Barrow , Mark T. Bilodeau , Christopher D. Cox , John C. Hartnett , Nathan R. Kett , Yiwei Li , Peter J. Manley , Jeffrey Melamed , William D. Shipe , B. Wesley Trotter , Amy Zartman
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; Gerard M. Devlin
- International Application: PCT/US2009/063030 WO 20091103
- International Announcement: WO2010/056564 WO 20100520
- Main IPC: A61K31/551
- IPC: A61K31/551 ; A61K31/5355 ; A61K31/497 ; A61K31/519 ; A61K31/4412 ; A61K31/4704 ; C07D243/08 ; C07D413/14 ; C07D471/04 ; C07D401/14 ; C07D401/12 ; C07D405/14
Abstract:
The present invention is directed to quinolone compounds which are antagonists of neuropeptide S receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which the neuropeptide S receptor is involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the neuropeptide S receptor is involved.
Public/Granted literature
- US20110212946A1 Quinolone Neuropeptide S Receptor Antagonists Public/Granted day:2011-09-01
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