Invention Grant
- Patent Title: Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
- Patent Title (中): 嘧啶环戊烷作为AKT蛋白激酶抑制剂
-
Application No.: US12667850Application Date: 2008-07-03
-
Publication No.: US08377937B2Publication Date: 2013-02-19
- Inventor: Josef R. Bencsik , James F. Blake , Nicholas C. Kallan , Ian S. Mitchell , Keith L. Spencer , Dengming Xiao , Rui Xu , Christine Chabot , Jun Liang , Brian S. Safina
- Applicant: Josef R. Bencsik , James F. Blake , Nicholas C. Kallan , Ian S. Mitchell , Keith L. Spencer , Dengming Xiao , Rui Xu , Christine Chabot , Jun Liang , Brian S. Safina
- Applicant Address: US CO Boulder US CA South San Francisco
- Assignee: Array BioPharma Inc.,Genentech, Inc.
- Current Assignee: Array BioPharma Inc.,Genentech, Inc.
- Current Assignee Address: US CO Boulder US CA South San Francisco
- Agency: Viksnins Harris & Padys PLLP
- International Application: PCT/US2008/069147 WO 20080703
- International Announcement: WO2009/006569 WO 20090108
- Main IPC: C07D239/70
- IPC: C07D239/70 ; A61K31/517
Abstract:
The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
Public/Granted literature
- US20110160221A1 PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS Public/Granted day:2011-06-30
Information query
