Invention Grant
US08283351B2 Cyclic and acyclic hydrazine derivatives compositions including them and uses thereof
有权
包括它们的环状和非环状肼衍生物组合物及其应用
- Patent Title: Cyclic and acyclic hydrazine derivatives compositions including them and uses thereof
- Patent Title (中): 包括它们的环状和非环状肼衍生物组合物及其应用
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Application No.: US12058371Application Date: 2008-03-28
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Publication No.: US08283351B2Publication Date: 2012-10-09
- Inventor: Michael Geoffrey Neil Russell , Huw David Vater , Jacqueline Anne Macritchie , Kevin James Doyle , David Brown , Joanne Peach
- Applicant: Michael Geoffrey Neil Russell , Huw David Vater , Jacqueline Anne Macritchie , Kevin James Doyle , David Brown , Joanne Peach
- Applicant Address: US CA South San Francisco
- Assignee: Institute for OneWorld Health
- Current Assignee: Institute for OneWorld Health
- Current Assignee Address: US CA South San Francisco
- Agency: Foley & Lardner LLP
- Agent Antoinette F. Konski; Photon Rao
- Main IPC: A01N43/56
- IPC: A01N43/56 ; A61K31/415 ; C07D401/00
Abstract:
The present invention relates to compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of the functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a cyclic or acyclic hydrazine derivative including those of formulas II or III: or compositions thereof, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.
Public/Granted literature
- US20080269206A1 CFTR INHIBITOR COMPOUNDS AND USES THEREOF Public/Granted day:2008-10-30
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