发明授权
- 专利标题: Means for inhibiting the expression of protein kinase 3
- 专利标题(中): 抑制蛋白激酶3表达的方法
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申请号: US12307052申请日: 2007-07-20
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公开(公告)号: US08232256B2公开(公告)日: 2012-07-31
- 发明人: Jorg Kaufmann , Oliver Keil , Ansgar Santel
- 申请人: Jorg Kaufmann , Oliver Keil , Ansgar Santel
- 申请人地址: DE Berlin
- 专利权人: Silence Therapeutics AG
- 当前专利权人: Silence Therapeutics AG
- 当前专利权人地址: DE Berlin
- 代理机构: Saliwanchik, Lloyd & Eisenschenk
- 优先权: EP06015262 20060721
- 国际申请: PCT/EP2007/006492 WO 20070720
- 国际公布: WO2008/009477 WO 20080124
- 主分类号: C12N15/11
- IPC分类号: C12N15/11 ; C12N5/00 ; C07H21/02 ; C07H21/04 ; C12Q1/68 ; C12P19/34
摘要:
The present invention is related to a nucleic acid molecule and uses thereof. The nucleic acid molecule comprises a double-stranded structure, whereby the double-stranded structure comprises a first strand and a second strand, whereby the first strand comprises a first stretch of contiguous nucleotides and said first stretch is at least partially complementary to a target nucleic acid, and whereby the second strand comprises a second stretch of contiguous nucleotides and said second stretch is at least partially complementary to the first stretch, whereby the first stretch comprises a nucleic acid sequence which is at least partially complementary to a nucleotide core sequence of the nucleic acid sequence according to SEQ ID NO:1 (NM_013355).
公开/授权文献
- US20090304678A1 Means for Inhibiting the Expression of Protein Kinase 3 公开/授权日:2009-12-10
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