Invention Grant
- Patent Title: SiRNA targeting catenin, beta-1 (CTNNB1)
- Patent Title (中): 靶向连环蛋白，β-1（CTNNB1）
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Application No.: US11980210Application Date: 2007-10-30
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Publication No.: US08198427B1Publication Date: 2012-06-12
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Dorf & Nelson, LLP
- Agent Scott D. Locke, Esq.
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/04
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for CTNNB1.
Public/Granted literature
- US20120136144A1 SIRNA TARGETING CATENIN, BETA-1 (CTNNB1) Public/Granted day:2012-05-31
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