发明授权
US08088624B2 Method of detecting thrombosis by measuring von Willenbrand factor-cleaving protease
有权
通过测量von Willebrand因子切割蛋白酶检测血栓形成的方法
- 专利标题: Method of detecting thrombosis by measuring von Willenbrand factor-cleaving protease
- 专利标题(中): 通过测量von Willebrand因子切割蛋白酶检测血栓形成的方法
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申请号: US10584425申请日: 2004-12-22
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公开(公告)号: US08088624B2公开(公告)日: 2012-01-03
- 发明人: Tomoko Ono , Kenji Soejima , Masaki Hirashima , Wataru Morikawa , Yoichi Sakata
- 申请人: Tomoko Ono , Kenji Soejima , Masaki Hirashima , Wataru Morikawa , Yoichi Sakata
- 申请人地址: JP
- 专利权人: Mitsubishi Kagaku Iatron, Inc.
- 当前专利权人: Mitsubishi Kagaku Iatron, Inc.
- 当前专利权人地址: JP
- 代理机构: Heslin Rothenberg Farley & Mesiti P.C.
- 代理商 Brian E. Reese
- 优先权: JP2003-425706 20031222
- 国际申请: PCT/JP2004/019226 WO 20041222
- 国际公布: WO2005/062054 WO 20050707
- 主分类号: G01N33/86
- IPC分类号: G01N33/86 ; G01N33/53 ; G01N33/00
摘要:
A method of detecting thrombosis or the degree of thrombophilia by measuring a von Willebrand factor cleaving protease, and a kit for detecting thrombosis or the degree of thrombophilia, comprising an antibody or a fragment thereof specifically binding to a von Willebrand factor-cleaving protease, are disclosed. The detection method and the detection kit have an excellent convenience, rapidity, and specificity.
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