发明授权
US07727969B2 Controlled release nanoparticle having bound oligonucleotide for targeted delivery
有权
具有用于靶向递送的结合寡核苷酸的受控释放纳米颗粒
- 专利标题： Controlled release nanoparticle having bound oligonucleotide for targeted delivery
- 专利标题（中）： 具有用于靶向递送的结合寡核苷酸的受控释放纳米颗粒
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申请号： US10456978申请日： 2003-06-06
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公开(公告)号： US07727969B2公开(公告)日： 2010-06-01
- 发明人: Omid C. Farokhzad , Sang Yong Jon , Robert S. Langer
- 申请人： Omid C. Farokhzad , Sang Yong Jon , Robert S. Langer
- 申请人地址： US MA Cambridge
- 专利权人： Massachusetts Institute of Technology
- 当前专利权人： Massachusetts Institute of Technology
- 当前专利权人地址： US MA Cambridge
- 代理机构： Lahive & Cockfield, LLP
- 代理商 Brian C. Trinque
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; A61K9/14 ; C12Q1/68 ; C12N11/08 ; C12N11/04 ; G01N33/545 ; G01N33/549 ; A61K38/00 ; C07K17/04 ; C07K17/08
摘要：
The present invention relates to a conjugate that includes a nucleic acid ligand bound to a controlled release polymer system, a pharmaceutical composition that contains the conjugate, and methods of treatment using the conjugate. The controlled release polymer system includes an agent such as a therapeutic, diagnostic, prognostic, or prophylactic agent. The nucleic acid ligand that is bound to the controlled release polymer system, binds selectively to a target, such as a cell surface antigen, and thereby delivers the controlled release polymer system to the target.
公开/授权文献
- US20040247680A1 Targeted delivery of controlled release polymer systems 公开/授权日：2004-12-09
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