Invention Grant
US07563897B2 Naphthalene diimide-Zn(II) complex having selectivity for pyrophosphate, preparation method thereof and detecting method of pyrophosphate using the same
有权
对焦磷酸盐具有选择性的萘二酰亚胺-Zn（II）络合物及其制备方法和使用其的焦磷酸盐的检测方法
- Patent Title: Naphthalene diimide-Zn(II) complex having selectivity for pyrophosphate, preparation method thereof and detecting method of pyrophosphate using the same
- Patent Title (中): 对焦磷酸盐具有选择性的萘二酰亚胺-Zn（II）络合物及其制备方法和使用其的焦磷酸盐的检测方法
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Application No.: US11968120Application Date: 2007-12-31
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Publication No.: US07563897B2Publication Date: 2009-07-21
- Inventor: Ju Young Yoon , Ha Na Lee , Sook Kyung Kim
- Applicant: Ju Young Yoon , Ha Na Lee , Sook Kyung Kim
- Applicant Address: KR Seoul
- Assignee: EWHA University-Industry Collaboration Foundation
- Current Assignee: EWHA University-Industry Collaboration Foundation
- Current Assignee Address: KR Seoul
- Agency: Lucas & Mercanti, LLP
- Main IPC: C07F15/00
- IPC: C07F15/00 ; C12Q1/68 ; G01N33/53
Abstract:
The present invention provides a novel fluorescent chemosensor including a naphthalene diimide-Zn(II) complex, which can efficiently recognize pyrophosphate (PPi) at pH 7.4. The fluorescent chemosensor exhibits a new kind of excimer fluorescence, which is selective for PPi in 100% aqueous solution. Further, since the naphthalene diimide-Zn(II) complex of the present invention does not couple with inorganic phosphate (Pi) or adenosine triphosphate (ATP) and has high selectivity for PPi, it can be usefully used to detect pyrophosphate (PPi), which serves to transfer signals and store energy in living organisms.
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