发明授权
US07495006B2 2′ and 3′-substituted cyclobutyl nucleoside analogs for the treatment of viral infections and abnormal cellular proliferation
有权
2'和3'-取代的环丁基核苷类似物用于治疗病毒感染和异常细胞增殖
- 专利标题： 2′ and 3′-substituted cyclobutyl nucleoside analogs for the treatment of viral infections and abnormal cellular proliferation
- 专利标题（中）： 2'和3'-取代的环丁基核苷类似物用于治疗病毒感染和异常细胞增殖
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申请号： US11301326申请日： 2005-12-08
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公开(公告)号： US07495006B2公开(公告)日： 2009-02-24
- 发明人: Dennis C. Liotta , Shuli Mao , Michael Hager
- 申请人： Dennis C. Liotta , Shuli Mao , Michael Hager
- 申请人地址： US GA Atlanta
- 专利权人： Emory University
- 当前专利权人： Emory University
- 当前专利权人地址： US GA Atlanta
- 代理机构： King & Spalding
- 主分类号： A61K31/505
- IPC分类号： A61K31/505 ; A61K31/506 ; A61K31/513 ; A61K31/52 ; A61K31/522 ; C07F9/113 ; C07F9/117 ; C07D239/47 ; C07D239/48 ; C07D473/02 ; C07D473/04 ; C07D473/18 ; C07D473/26 ; C07D473/32 ; C07D473/34
摘要：
Provided are cyclobutyl nucleosides and methods for their use in treatment of infections including Retroviridae (including HIV), Hepadnaviridae (including HBV), or Flaviviridae (including BVDV and HCV) infection, or conditions related to abnormal cellular proliferation, in a host, including animals, and especially humans.
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