发明授权
- 专利标题: Solid-phase reactions
- 专利标题(中): 固相反应
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申请号: US10197189申请日: 2002-07-17
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公开(公告)号: US07485443B2公开(公告)日: 2009-02-03
- 发明人: Priscilla Wilkins Stevens , David Kelso , Victor Lyamichev , Jeff Hall , Bruce P. Neri , Robert W. Kwiatkowski, Jr. , Lloyd Smith
- 申请人: Priscilla Wilkins Stevens , David Kelso , Victor Lyamichev , Jeff Hall , Bruce P. Neri , Robert W. Kwiatkowski, Jr. , Lloyd Smith
- 申请人地址: US IL Evanston
- 专利权人: Northwestern University
- 当前专利权人: Northwestern University
- 当前专利权人地址: US IL Evanston
- 代理机构: Casimir Jones, S.C.
- 主分类号: C12P19/34
- IPC分类号: C12P19/34
摘要:
The present invention relates to systems, compositions, and methods for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. The present invention relates to methods for attaching nucleic acids to solid supports and modifying nucleic acids. For example, in some embodiments, the 5′ nuclease activity of a cleavage agent is used to cleave a cleavage structure formed on the solid support, the occurrence of the cleavage event indicating the presence of specific nucleic acid sequences.
公开/授权文献
- US20030119020A1 Solid-phase reactions 公开/授权日:2003-06-26
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