Invention Grant
US07449300B2 Detection of antibodies specific for B7-H1 in subjects with diseases or pathological conditions mediated by activated T cells
有权
检测受活化T细胞介导的疾病或病理状况受试者B7-H1特异性抗体
- Patent Title: Detection of antibodies specific for B7-H1 in subjects with diseases or pathological conditions mediated by activated T cells
- Patent Title (中): 检测受活化T细胞介导的疾病或病理状况受试者B7-H1特异性抗体
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Application No.: US10719477Application Date: 2003-11-21
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Publication No.: US07449300B2Publication Date: 2008-11-11
- Inventor: Lieping Chen , Scott E. Strome
- Applicant: Lieping Chen , Scott E. Strome
- Applicant Address: US MN Rochester
- Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee Address: US MN Rochester
- Agency: Millen, White, Zelano, Branigan, P.C.
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
The invention provides methods of removing B7-H1-specific antibodies from a body fluid (e.g., blood), methods of diagnosing and treating diseases and pathological conditions mediated by activated T cells, methods for screening for compounds that inhibit binding of a B7-H1-specific antibody to B7-H1, and methods of designing compounds that inhibit binding of a B7-H1-specific antibody to B7-H1.
Public/Granted literature
- US20040180047A1 Autoantibodies specific for B7-H1 Public/Granted day:2004-09-16
Information query
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