发明授权
US07410638B1 Bacterial strains, genes and enzymes for control of bacterial diseases by quenching quorum-sensing signals
失效
细菌菌株，基因和酶通过淬灭群体感应信号来控制细菌性疾病
- 专利标题： Bacterial strains, genes and enzymes for control of bacterial diseases by quenching quorum-sensing signals
- 专利标题（中）： 细菌菌株，基因和酶通过淬灭群体感应信号来控制细菌性疾病
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申请号： US10362569申请日： 2000-08-23
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公开(公告)号： US07410638B1公开(公告)日： 2008-08-12
- 发明人: Lianhui Zhang , Yihu Dong , Haibao Zhang , Jinling Xu
- 申请人： Lianhui Zhang , Yihu Dong , Haibao Zhang , Jinling Xu
- 申请人地址： SG Singapore
- 专利权人： Institute of Molecular Agrobiology
- 当前专利权人： Institute of Molecular Agrobiology
- 当前专利权人地址： SG Singapore
- 代理机构： Rothwell, Figg, Ernst & Manbeck, P.C.
- 国际申请： PCT/SG00/00123 WO 20000823
- 国际公布： WO02/16623 WO 20020228
- 主分类号： C12N9/54
- IPC分类号： C12N9/54 ; C12N15/00 ; C12N1/20 ; C07H21/04 ; A61K38/48
摘要：
The present invention relates to isolated nucleic acid molecules encoding an autoinducer inactivation protein, wherein the encoded protein comprises an amino acid sequence selected from the group consisting of 104HXHXDH109˜60aa˜H169˜21aa˜D191 and 103HXHXDH108˜72aa˜H180˜21aa˜D202, and to expression vectors and transformed plant and animal cells comprising the same. The proteins encoded by these nucleic acid molecules provide to a susceptible plant or animal increased resistance to a disease the virulence of which is regulated by autoinducers. Also provided are methods of increasing disease resistance in susceptible plants and animals.
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