发明授权
US07122557B2 Sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds as factor Xa inhibitors
有权
含磺酰基 - 脒基和四氢嘧啶基的化合物作为因子Xa抑制剂
- 专利标题： Sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds as factor Xa inhibitors
- 专利标题（中）： 含磺酰基 - 脒基和四氢嘧啶基的化合物作为因子Xa抑制剂
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申请号： US10801518申请日： 2004-03-16
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公开(公告)号： US07122557B2公开(公告)日： 2006-10-17
- 发明人: Donald J. Pinto , Jennifer X. Qiao , Timur Gungor , Patrick Y. S. Lam , Yun-Long Li
- 申请人： Donald J. Pinto , Jennifer X. Qiao , Timur Gungor , Patrick Y. S. Lam , Yun-Long Li
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 Jing G. Sun; David H. Vance
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; C07D471/04
摘要：
The present application describes sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds and derivatives thereof of Formula I: P4-P-M-M4I or pharmaceutically acceptable salt forms thereof, wherein M is a ring, P is an optional ring, and P4 and M4 are as defined below. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
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