发明授权
- 专利标题： Monoclonal antibody reacting specifically reacting with Fas ligand and production process thereof
- 专利标题（中）： 与Fas配体特异性反应的单克隆抗体及其制备方法
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申请号： US08913555申请日： 1996-03-21
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公开(公告)号： US06946255B1公开(公告)日： 2005-09-20
- 发明人: Nobuhiko Kayagaki , Hideo Yagita , Ko Okumura , Motomi Nakata
- 申请人： Nobuhiko Kayagaki , Hideo Yagita , Ko Okumura , Motomi Nakata
- 申请人地址： JP Tokyo
- 专利权人： Ko Okumura
- 当前专利权人： Ko Okumura
- 当前专利权人地址： JP Tokyo
- 代理机构： McDermott Will & Emery LLP
- 优先权： JP7/087420 19950320; JP7/303492 19951027
- 国际申请： PCT/JP96/00734 WO 19960321
- 国际公布： WO96/29350 WO 19960926
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K16/28 ; C12P21/08 ; G01N33/53 ; C07K21/08
摘要：
The invention provides monoclonal antibodies, which specifically react with a Fas ligand, or active fragments thereof, a production process of the monoclonal antibodies, which specifically react with a Fas ligand, hybridomas separately producing a monoclonal antibody, which specifically reacts with a Fas ligand present on a cell surface, a method of detecting a Fas ligand in a solution, and a kit for use in detecting a Fas ligand, comprising plurality of monoclonal antibodies against Fas ligand in combination.
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