发明授权
US06864266B2 4-piperidinyl alkyl amine derivatives as muscarinic receptor antagonists
失效
4-哌啶基烷基胺衍生物作为毒蕈碱受体拮抗剂
- 专利标题： 4-piperidinyl alkyl amine derivatives as muscarinic receptor antagonists
- 专利标题（中）： 4-哌啶基烷基胺衍生物作为毒蕈碱受体拮抗剂
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申请号： US10611193申请日： 2003-07-01
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公开(公告)号： US06864266B2公开(公告)日： 2005-03-08
- 发明人: Christine E. Brotherton-Pleiss , Ann Marie Madera , Robert James Weikert
- 申请人： Christine E. Brotherton-Pleiss , Ann Marie Madera , Robert James Weikert
- 申请人地址： US CA Palo Alto
- 专利权人： Syntex (U.S.A.) LLC
- 当前专利权人： Syntex (U.S.A.) LLC
- 当前专利权人地址： US CA Palo Alto
- 代理商 Brian J. Buckwalter
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; A61K31/4525 ; A61K31/4535 ; A61K31/454 ; A61K31/4545 ; A61K31/496 ; A61K31/5377 ; A61P1/00 ; A61P1/06 ; A61P1/12 ; A61P11/00 ; A61P11/06 ; A61P13/02 ; A61P13/10 ; A61P21/00 ; A61P25/02 ; A61P25/28 ; A61P43/00 ; C07D211/26 ; C07D211/92 ; C07D401/06 ; C07D401/12 ; C07D405/06 ; C07D409/06 ; C07D409/12 ; C07D413/06 ; C07D413/14 ; C07D211/06
摘要：
This invention relates to the (R)-isomers of compounds which are generally muscarinic receptor antagonists and which are represented by Formula I: wherein p, R1, R2, R3 and A are as defined in the specification, or individual isomers, racemic or non-racemic mixtures of isomers, or acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use and preparation as therapeutic drugs.
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