发明授权
US06498151B2 Aryldifluoromethylphosphonic acids with sulfur-containing substituents as PTP-1B inhibitors
失效
具有含硫取代基的芳基二氟甲基膦酸作为PTP-1B抑制剂
- 专利标题： Aryldifluoromethylphosphonic acids with sulfur-containing substituents as PTP-1B inhibitors
- 专利标题（中）： 具有含硫取代基的芳基二氟甲基膦酸作为PTP-1B抑制剂
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申请号： US09813489申请日： 2001-03-21
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公开(公告)号： US06498151B2公开(公告)日： 2002-12-24
- 发明人: Chun Sing Li , Christopher Bayly , Jacques Yves Gauthier , Yves Leblanc , Cheuk Kun Lau , Patrick Roy , Michel Therien , Zhaoyin Wang , Claude Dufresne , Rejean Fortin
- 申请人： Chun Sing Li , Christopher Bayly , Jacques Yves Gauthier , Yves Leblanc , Cheuk Kun Lau , Patrick Roy , Michel Therien , Zhaoyin Wang , Claude Dufresne , Rejean Fortin
- 主分类号： C07D23995
- IPC分类号： C07D23995
摘要：
The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes.
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