发明授权
- 专利标题: Compositions of iodophenyl esters for X-ray visualization of the gastrointestinal tract
- 专利标题(中): 碘苯酯的组合物用于胃肠道X线显像
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申请号: US40823申请日: 1993-03-31
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公开(公告)号: US5318769A公开(公告)日: 1994-06-07
- 发明人: Edward R. Bacon , Sol J. Daum , Kimberly G. Estep , Kurt A. Josef , Brent D. Douty , Carl R. Illig
- 申请人: Edward R. Bacon , Sol J. Daum , Kimberly G. Estep , Kurt A. Josef , Brent D. Douty , Carl R. Illig
- 申请人地址: PA Malvern
- 专利权人: Sterling Winthrop Inc.
- 当前专利权人: Sterling Winthrop Inc.
- 当前专利权人地址: PA Malvern
- 主分类号: A61K49/04
- IPC分类号: A61K49/04 ; C07C69/017 ; C07C69/63 ; C07C69/675 ; C07C69/708 ; C07C69/74 ; C07C69/773 ; C07C255/55 ; C07C309/65 ; C07C309/67 ; C07C309/68 ; C07C309/71 ; C07C309/72 ; C07C69/00 ; C07C69/66
摘要:
Disclosed are contrast agents of the formula ##STR1## contained in aqueous compositions and methods for their use in diagnostic radiology of the gastrointestinal tract whereinX= ##STR2## Z=H, halo, C.sub.1 -C.sub.20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups;R=C.sub.1 -C.sub.25 alkyl, cycloalkyl, aryl, or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, lower-alkoxy, hydroxy, carboxy or lower-alkoxy carbonyl, lower-alkenyl, lower-alkynyl, lower-alkylene, lower-alkoxy-carbonyloxy;n=1-5;y=0-4; andw=1-4in an aqueous pharmaceutically acceptable carrier.
公开/授权文献
- USD377587S Handle for spoons 公开/授权日:1997-01-28
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