发明授权
- 专利标题: Tricyclic compounds and processes
- 专利标题(中): 三元化合物和方法
-
申请号: US32260073申请日: 1973-01-10
-
公开(公告)号: US3860615A公开(公告)日: 1975-01-14
- 发明人: REY-BELLET GERALD , SPIEGELBERG HANS
- 申请人: HOFFMANN LA ROCHE
- 专利权人: Hoffmann La Roche
- 当前专利权人: Hoffmann La Roche
- 优先权: CH196964 1964-02-18; CH1472067 1964-12-04; CH1570964 1964-12-04
- 主分类号: A61K31/00
- IPC分类号: A61K31/00 ; C07C51/15 ; C07C51/373 ; C07C61/39 ; C07C62/34 ; C07C62/38 ; C07C65/34 ; C07D213/40 ; C07D295/185 ; C07D317/72 ; C07D13/04
摘要:
Dibenzo(a,d)cyclohepta(1,4,6)trienes bearing in the 5-position, substituents such as, for example, oxo- or 3''-lower alkoxyalkylidene and in the 10-position, substituents such as, for example, carbonyl, thiocarbonyl or guanyl radicals, for instance, 5-(3''-lower alkoxypropylidene)-dibenzo(a,d)cyclohepta (1,4,6)triene 10-carboxylic acid di-(lower alkyl)amides and dibenzo(a,d)cyclohepta(1,4,6)trien-5-one 10-carboxylic acid cyclic amides, prepared, inter alia, from 5-(3''-lower alkoxypropylidene)-dibenzo(a,d)cyclohepta,(1,4,6)triene 10carboxylic acid, 10-halocarbonyl-5-(3''-lower alkoxypropylidene)dibenzo(a,d)cyclohepta(1,4,6)triene or dibenzo(a,d)cyclohepta(1,4,6)trien-5-one 10-carboxylic acid halide, are described. The end products are useful as antidepressants.
信息查询