Invention Application
- Patent Title: TEXAPHYRIN DERIVATIVES FOR MANGANESE CHEMOTHERAPY, PHOTOACOUSTIC IMAGING, AND PHOTOTHERMAL THERAPY
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Application No.: US18041470Application Date: 2021-08-14
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Publication No.: US20250034158A1Publication Date: 2025-01-30
- Inventor: Jonathan L. SESSLER , Adam C. SEDGWICK , Gregory THIABAUD , Jonathan ARAMBULA
- Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- International Application: PCT/US21/46049 WO 20210814
- Main IPC: C07D487/22
- IPC: C07D487/22 ; A61K31/555 ; A61K41/00 ; A61K49/22
Abstract:
The present disclosure relates to manganese containing texaphyrin compounds of the formula (I). Wherein the variables are as described herein. The present disclosure also provides pharmaceutical compositions of the compounds. Also, provided herein are methods of using the compounds in the treatment of cancer including platinum resistant cancer.
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