- 专利标题： TREATMENT OF CANCER ASSOCIATED WITH VARIANT NOVEL OPEN READING FRAMES
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申请号： US18267223申请日： 2021-12-15
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公开(公告)号： US20240060070A1公开(公告)日： 2024-02-22
- 发明人: Sudhakaran PRABAKARAN
- 申请人： Cambridge Enterprise Limited , International Centre for Genetic Engineering and Biotechnology
- 申请人地址： GB Cambridge
- 专利权人： Cambridge Enterprise Limited,International Centre for Genetic Engineering and Biotechnology
- 当前专利权人： Cambridge Enterprise Limited,International Centre for Genetic Engineering and Biotechnology
- 当前专利权人地址： GB Cambridge
- 国际申请： PCT/IB2021/061804 2021.12.15
- 进入国家日期： 2023-06-14
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61K31/4155 ; A61K31/4709 ; C07K14/82 ; C12N15/86
摘要：
The present application features methods of treating a cancer associated with a genetic variant. The genetic variant is also present within a novel open reading frame (nORF) associated with the gene in which the variant leads to increased or reduced expression of the variant nORF.
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