Invention Publication
- Patent Title: KRAS G12D INHIBITORS
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Application No.: US18020013Application Date: 2021-08-03
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Publication No.: US20230339976A1Publication Date: 2023-10-26
- Inventor: Xiaolun Wang , Matthew Arnold Marx , John David Lawson , Shelley Allen , Patrick Michael Barbour , James Francis Blake , Joshua Ryan Dahlke , Donghua Dai , Jay Bradford Fell , John Peter Fischer , Sherif Hosam Hassanien , Michael Christopher Hilton , Macedonio Junior Mejia , Jacob Matthew O’Leary , Tony Pisal Tang
- Applicant: Mirati Therapeutics, Inc. , Array BioPharma Inc.
- Applicant Address: US CA San Diego
- Assignee: Mirati Therapeutics, Inc.,Array BioPharma Inc.
- Current Assignee: Mirati Therapeutics, Inc.,Array BioPharma Inc.
- Current Assignee Address: US CA San Diego
- International Application: PCT/US2021/044308 2021.08.03
- Date entered country: 2023-02-06
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D519/00

Abstract:
The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.
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