Described herein is a server computing system that controls an autonomous vehicle to perform an operation to at least one of measure or isolate an effect of a variable on an actual power consumption by the autonomous vehicle. Data indicative of the actual power consumption, which is generated based on the operation, and data indicative of a projected power consumption, which is accumulated based on prior execution of the operation by a same or different autonomous vehicle, is received by the server computing system to determine whether an energy efficiency of the autonomous vehicle is degraded. The operation may be performed to identify a degraded vehicle system or component of the autonomous vehicle or to identify an autonomous vehicle in a fleet of autonomous vehicles for which further analysis is desirable. An output is generated by the server computing system that is indicative of the energy efficiency prognostics.