- 专利标题： SPIRO COMPOUNDS AS INHIBITORS OF KRAS
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申请号： US17153065申请日： 2021-01-20
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公开(公告)号： US20210230162A1公开(公告)日： 2021-07-29
- 发明人: Le Zhao , Xiaozhao Wang , Wenyu Zhu , Haolin Yin , Liangxing Wu , Wenqing Yao
- 申请人： Incyte Corporation
- 申请人地址： US DE Wilmington
- 专利权人： Incyte Corporation
- 当前专利权人： Incyte Corporation
- 当前专利权人地址： US DE Wilmington
- 主分类号： C07D471/20
- IPC分类号： C07D471/20 ; C07D491/20 ; C07D471/22 ; C07D498/20
摘要：
Disclosed are compounds of Formula I, methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.
公开/授权文献
- US11530218B2 Spiro compounds as inhibitors of KRAS 公开/授权日：2022-12-20
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