- 专利标题： TGF BETA RECEPTOR ANTAGONISTS
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申请号： US15755636申请日： 2016-08-30
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公开(公告)号： US20180243312A1公开(公告)日： 2018-08-30
- 发明人: Robert M. BORZILLERI , Brian E. Fink , Lalgudi S. Harikrishnan , Jayakumar Sankara Warrier
- 申请人： BRISTOL-MYERS SQUIBB COMPANY
- 国际申请： PCT/US2016/049351 WO 20160830
- 主分类号： A61K31/53
- IPC分类号： A61K31/53 ; A61K35/02 ; A61P35/00
摘要：
The invention relates generally to compounds that modulate the activity of TGFBETA R-1 and TGFBETA R-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
公开/授权文献
- US10292985B2 TGF beta receptor antagonists 公开/授权日：2019-05-21
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