发明申请
US20160026752A1 Systems And Methods For Comprehensive Analysis Of Molecular Profiles Across Multiple Tumor And Germline Exomes 审中-公开
用于多个肿瘤和种系异常的分子谱综合分析的系统和方法

Systems And Methods For Comprehensive Analysis Of Molecular Profiles Across Multiple Tumor And Germline Exomes
摘要:
Omics patient data are analyzed using sequences or diff objects of tumor and matched normal tissue to identify patient and disease specific mutations, using transcriptomic data to identify expression levels of the mutated genes, and pathway analysis based on the so obtained omic data to identify specific pathway characteristics for the diseased tissue. Most notably, many different tumors have shared pathway characteristics, and identification of a pathway characteristic of a tumor may thus indicate effective treatment options ordinarily not considered when tumor analysis is based on anatomical tumor type only.
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